Using a clinical narrative-aware pre-trained language model for predicting emergency department patient disposition and unscheduled return visits

IF 4 2区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Journal of Biomedical Informatics Pub Date : 2024-05-19 DOI:10.1016/j.jbi.2024.104657
Tzu-Ying Chen , Ting-Yun Huang , Yung-Chun Chang
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Abstract

The increasing prevalence of overcrowding in Emergency Departments (EDs) threatens the effective delivery of urgent healthcare. Mitigation strategies include the deployment of monitoring systems capable of tracking and managing patient disposition to facilitate appropriate and timely care, which subsequently reduces patient revisits, optimizes resource allocation, and enhances patient outcomes. This study used ∼ 250,000 emergency department visit records from Taipei Medical University-Shuang Ho Hospital to develop a natural language processing model using BlueBERT, a biomedical domain-specific pre-trained language model, to predict patient disposition status and unplanned readmissions. Data preprocessing and the integration of both structured and unstructured data were central to our approach. Compared to other models, BlueBERT outperformed due to its pre-training on a diverse range of medical literature, enabling it to better comprehend the specialized terminology, relationships, and context present in ED data. We found that translating Chinese-English clinical narratives into English and textualizing numerical data into categorical representations significantly improved the prediction of patient disposition (AUROC = 0.9014) and 72-hour unscheduled return visits (AUROC = 0.6475). The study concludes that the BlueBERT-based model demonstrated superior prediction capabilities, surpassing the performance of prior patient disposition predictive models, thus offering promising applications in the realm of ED clinical practice.

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使用临床叙事感知预训练语言模型预测急诊科病人处置和计划外回访。
急诊科(ED)人满为患的现象日益普遍,威胁着紧急医疗服务的有效提供。缓解策略包括部署能够跟踪和管理病人处置情况的监控系统,以促进适当和及时的护理,从而减少病人再次就诊,优化资源分配,提高病人的治疗效果。本研究利用台北医学大学双和医院的 250,000 份急诊科就诊记录,使用生物医学领域特定的预训练语言模型 BlueBERT 开发了一个自然语言处理模型,用于预测患者处置状态和非计划再入院情况。数据预处理以及结构化和非结构化数据的整合是我们方法的核心。与其他模型相比,BlueBERT 的表现更胜一筹,这得益于它对各种医学文献的预训练,使其能够更好地理解急诊室数据中的专业术语、关系和上下文。我们发现,将中英文临床叙述翻译成英文,并将数字数据文本化为分类表示,可显著改善对患者处置(AUROC = 0.9014)和 72 小时计划外回访(AUROC = 0.6475)的预测。研究得出结论,基于 BlueBERT 的模型显示出卓越的预测能力,超越了之前的患者处置预测模型,因此在急诊室临床实践中具有广阔的应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Biomedical Informatics
Journal of Biomedical Informatics 医学-计算机:跨学科应用
CiteScore
8.90
自引率
6.70%
发文量
243
审稿时长
32 days
期刊介绍: The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.
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