Ankle fracture open reduction and internal fixation in patients with cerebral palsy.

IF 3.8 2区 医学 Q1 CLINICAL NEUROLOGY Developmental Medicine and Child Neurology Pub Date : 2024-11-01 Epub Date: 2024-05-21 DOI:10.1111/dmcn.15958
Meera M Dhodapkar, Ally Yang, Will Jiang, Scott J Halperin, David B Frumberg, Jonathan N Grauer
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Abstract

Aim: To examine patients with cerebral palsy (CP) undergoing open reduction and internal fixation (ORIF) for ankle fractures.

Method: This was a retrospective study of adult patients undergoing ankle fracture ORIF for closed, isolated ankle fractures identified in between 2010 and 2021 in the Q1 PearlDiver M151 database. Patients with CP were identified with International Classification of Diseases (ICD)-9 and ICD-10 codes, and were matched to those without 1:10 on age, sex, and Elixhauser comorbidity index (ECI). Ninety-day adverse events were assessed with multivariable logistic regression.

Results: A total of 148 993 patients with isolated ankle fracture ORIF were identified, of whom 407 (0.27%) had CP. After matching, 3863 without CP were compared to 389 with CP. Patients with CP were at increased odds of: 90-day urinary tract infection (odds ratios [OR] 6.26), pneumonia (OR 3.50), minor adverse events (OR 3.46), sepsis (OR 3.30), any adverse events (OR 3.04), emergency department visits (OR 2.28), serious adverse events (OR 1.77), and prolonged length of stay more than 4 days (OR 22.44) (p < 0.001 for all).

Interpretation: Patients with CP undergoing ORIF for isolated, closed ankle fractures are at increased odds of several 90-day adverse events and prolonged length of stay compared to matched patients without CP.

What this paper adds: Patients with cerebral palsy (CP) undergoing ankle fracture open reduction and internal fixation (ORIF) were at increased odds of 90-day adverse events. Many of the 90-day adverse events related to previously described comorbidities associated with CP. Patients with CP undergoing ankle fracture ORIF experienced increased rates of prolonged length of stay.

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脑瘫患者踝关节骨折切开复位内固定术。
目的:研究接受开放复位内固定术(ORIF)治疗踝关节骨折的脑瘫(CP)患者:这是一项回顾性研究,研究对象是2010年至2021年期间在Q1 PearlDiver M151数据库中发现的因闭合性、孤立性踝关节骨折接受踝关节骨折切开复位内固定术的成年患者。CP患者根据国际疾病分类(ICD)-9和ICD-10代码进行识别,并根据年龄、性别和Elixhauser合并症指数(ECI)与非CP患者进行1:10配对。通过多变量逻辑回归对九十天不良事件进行了评估:共确定了 148 993 例孤立性踝关节骨折 ORIF 患者,其中 407 例(0.27%)患有 CP。配对后,3863 名无 CP 患者与 389 名有 CP 患者进行了比较。患有 CP 的患者发生以下情况的几率增加90 天尿路感染(几率比 [OR] 6.26)、肺炎(OR 3.50)、轻微不良事件(OR 3.46)、败血症(OR 3.30)、任何不良事件(OR 3.04)、急诊就诊(OR 2.28)、严重不良事件(OR 1.77)和住院时间延长超过 4 天(OR 22.44)的几率增加:与无 CP 的匹配患者相比,因孤立性闭合性踝关节骨折接受 ORIF 的 CP 患者发生 90 天不良事件和住院时间延长的几率更高。
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来源期刊
CiteScore
7.80
自引率
13.20%
发文量
338
审稿时长
3-6 weeks
期刊介绍: Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.
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