Treatment of mixed and refractory post-tuberculosis tracheobronchial stenosis with L-shaped silicone stents: case series and a literature review.

IF 3.3 3区 医学 Q2 RESPIRATORY SYSTEM Therapeutic Advances in Respiratory Disease Pub Date : 2024-01-01 DOI:10.1177/17534666241254901
Changwen Zhang, Wentao Li, Yu Li, Ni Fang, Mingpeng Xu, Lan Ke, Lifang Li, Guangnan Liu
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Abstract

The two patients included in the study had mixed and refractory post-tuberculosis tracheobronchial stenosis (PTTS), having experienced unsuccessful interventional therapies such as balloon dilation and V-shaped stent placement before the operation. Following the secure placement of L-shaped silicone stents, examinations with a fiberbronchoscope during the first and third months post-operation revealed a significant reduction in bronchial mucosa inflammation for both patients. Additionally, the opening diameter of the upper and lower branch segments increased, and chest CT scans indicated a noticeable absorption of left pulmonary lesions. Three months post-operation, fiberbronchoscopy confirmed the stable fixation of the stent without any movement. The patients exhibited substantial improvements in pulmonary function, dyspnea index, and blood gas analysis, with no reported adverse complications. After 7 months, a follow-up fiberbronchoscope for one case revealed excellent stent fixation. Simultaneously, the chest CT scan indicated favorable re-expansion. The placement of L-shaped silicone stents proves effective in preventing displacement, alleviating airway stenosis or obstruction, and ensuring the safety and efficacy of PTTS treatment - particularly in cases where V-shaped silicone stent placement has failed. To our knowledge, this is the first study describing the L-shaped silicone stent in two patients with PTTS.

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用 L 型硅胶支架治疗混合型和难治性肺结核后气管支气管狭窄:病例系列和文献综述。
参与研究的两名患者均为肺结核后气管支气管狭窄(PTTS)混合型难治性患者,手术前曾经历过球囊扩张和 V 型支架置入等介入治疗,但均未获成功。在安全放置 L 型硅胶支架后,术后第一和第三个月的纤维支气管镜检查显示,两名患者的支气管粘膜炎症均明显减轻。此外,上下支段的开口直径增大,胸部 CT 扫描显示左肺病灶明显吸收。术后三个月,纤维支气管镜检查证实支架固定稳定,没有任何移动。患者的肺功能、呼吸困难指数和血气分析均有显著改善,无不良并发症报告。7 个月后,一个病例的纤维支气管镜随访显示支架固定良好。同时,胸部 CT 扫描也显示出良好的再扩张情况。事实证明,放置 L 型硅胶支架能有效防止移位,缓解气道狭窄或阻塞,确保 PTTS 治疗的安全性和有效性,尤其是在放置 V 型硅胶支架失败的病例中。据我们所知,这是首次在两名 PTTS 患者中使用 L 型硅胶支架的研究。
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来源期刊
CiteScore
6.90
自引率
0.00%
发文量
57
审稿时长
15 weeks
期刊介绍: Therapeutic Advances in Respiratory Disease delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of respiratory disease.
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