Efficacy of Radiofrequency Diathermy versus Focused Ultrasound Therapy, Both Combined with Intermittent Pneumatic Compression, for Edematous Fibrosclerotic Panniculopathy Treatment: A Randomized Intrasubject Assessor-Blind Trial

IF 3.7 4区医学 Q1 DERMATOLOGY Dermatologic Therapy Pub Date : 2024-04-27 DOI:10.1155/2024/9179759

V. Mihaiescu-Ion, J. A. Moral-Munoz, D. Lucena-Anton, F. J. Martin-Vega, M. Rebollo-Salas, I. M. Carmona-Barrientos

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Abstract

Background. Edematous fibrosclerotic panniculopathy (EFP), commonly known as cellulite, is a cosmetic concern affecting a large percentage of women. Radiofrequency diathermy (RFD) and focused ultrasound (FUS) are noninvasive treatments proposed for the reduction of EFP. Objective. This study aimed to evaluate the efficacy of RFD versus FUS, both combined with intermittent pneumatic compression (IPC) for the treatment of EFP in female thighs. Methods. A randomized intrasubject assessor-blind trial was conducted (NCT03474523) on 40 lower limbs of 20 women with EFP grades I, II, or III according to the Nürnberger & Müller scale. Each lower limb was randomly assigned to receive either seven RFD sessions or seven FUS sessions, both combined with IPC. Measurements were collected at baseline and post-treatment, including lower limb circumferences at different levels, weight, grade of EFP, and physical activity level. Results. Both RFD and FUS treatments, both combined with IPC, showed significant intragroup reduction in thigh circumference measurements for RFD at 15 cm (p = 0.001), 20 cm (p = 0.024), and midpoint (p = 0.008) and for FUS at 15 cm (p = 0.001), 20 cm (p = 0.010), midpoint (p = 0.008), 30 cm (p = 0.020), and 40 cm (p = 0.048). No statistically significant differences were observed between the two treatments. Weight did not change with treatment, and physical activity levels did not significantly affect EFP improvement. Conclusion. Both RFD and FUS, combined with IPC, were effective noninvasive methods for treating EFP. This study found that there was no significant difference between RFD and FUS in terms of efficacy in reducing EFP in the thighs. Therefore, both techniques can be used to treat EFP from a clinical perspective. Further studies with objective measurements are required to confirm these results and to guide clinical decision-making. This trial is registered with NCT03474523.

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射频透热疗法与聚焦超声波疗法（两者均结合间歇性气压疗法）治疗水肿性纤维硬化性泛发性肌病的疗效：随机受试者内评估者盲法试验

背景。水肿性纤维硬结症（EFP），俗称橘皮组织，是影响很大一部分女性的美容问题。射频透热疗法（RFD）和聚焦超声波疗法（FUS）是减少 EFP 的非侵入性疗法。研究目的本研究旨在评估射频透热疗法和聚焦超声波疗法的疗效，两种疗法均结合间歇性气压疗法（IPC）治疗女性大腿EFP。研究方法。根据 Nürnberger & Müller 量表，对患有 I、II 或 III 级 EFP 的 20 名女性的 40 个下肢进行了随机受试者内评估者盲法试验（NCT03474523）。每个下肢被随机分配接受七次 RFD 治疗或七次 FUS 治疗，两种治疗均结合 IPC。在基线和治疗后收集测量数据，包括不同水平的下肢周长、体重、EFP等级和体力活动水平。结果显示RFD和FUS治疗均结合了IPC，结果显示，RFD治疗组内大腿围测量值在15厘米（p = 0.001）、20厘米（p = 0.024）和中点（p = 0.008）处显著减少，FUS治疗组内大腿围测量值在15厘米（p = 0.001）、20厘米（p = 0.010）、中点（p = 0.008）、30厘米（p = 0.020）和40厘米（p = 0.048）处显著减少。两种处理之间没有发现明显的统计学差异。体重没有随治疗而改变，体力活动水平对 EFP 的改善也没有显著影响。结论RFD和FUS结合IPC是治疗EFP的有效无创方法。本研究发现，RFD 和 FUS 在减少大腿 EFP 方面的疗效没有明显差异。因此，从临床角度来看，这两种技术都可用于治疗 EFP。要证实这些结果并指导临床决策，还需要进一步的客观测量研究。该试验已注册为 NCT03474523。

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来源期刊

Dermatologic Therapy 医学-皮肤病学

CiteScore

7.00

自引率

8.30%

发文量

711

审稿时长

3 months

期刊介绍： Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.