Zoltán Szabó, Kitti Pankász, János Bozorádi, O. Hakkel, Szabolcs Bella, Bianka Fabinyi, Sandro Meucci, Péter Fürjes
{"title":"Microfluidic Cuvette for Near-Infrared Spectroscopy","authors":"Zoltán Szabó, Kitti Pankász, János Bozorádi, O. Hakkel, Szabolcs Bella, Bianka Fabinyi, Sandro Meucci, Péter Fürjes","doi":"10.3390/proceedings2024097209","DOIUrl":null,"url":null,"abstract":": We intend to develop an in situ near-infrared spectroscopic solution for monitoring the nutrient composition (e.g., lactate concentration) in microfluidic channels of organ-on-chip devices. In this work, the effects of the geometry, surface quality, and architecture of the micro-volume cuvettes were characterized and optimized considering the signal-to-noise ratio and sensitivity of the proposed spectroscopic method in case of aqueous solutions. The applicability of the micro-volume near-infrared spectroscopy method using this specially designed microfluidic cuvette was proven.","PeriodicalId":517679,"journal":{"name":"Eurosensors 2023","volume":" 13","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eurosensors 2023","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/proceedings2024097209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
: We intend to develop an in situ near-infrared spectroscopic solution for monitoring the nutrient composition (e.g., lactate concentration) in microfluidic channels of organ-on-chip devices. In this work, the effects of the geometry, surface quality, and architecture of the micro-volume cuvettes were characterized and optimized considering the signal-to-noise ratio and sensitivity of the proposed spectroscopic method in case of aqueous solutions. The applicability of the micro-volume near-infrared spectroscopy method using this specially designed microfluidic cuvette was proven.