Microfluidic Cuvette for Near-Infrared Spectroscopy

Zoltán Szabó, Kitti Pankász, János Bozorádi, O. Hakkel, Szabolcs Bella, Bianka Fabinyi, Sandro Meucci, Péter Fürjes
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Abstract

: We intend to develop an in situ near-infrared spectroscopic solution for monitoring the nutrient composition (e.g., lactate concentration) in microfluidic channels of organ-on-chip devices. In this work, the effects of the geometry, surface quality, and architecture of the micro-volume cuvettes were characterized and optimized considering the signal-to-noise ratio and sensitivity of the proposed spectroscopic method in case of aqueous solutions. The applicability of the micro-volume near-infrared spectroscopy method using this specially designed microfluidic cuvette was proven.
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用于近红外光谱分析的微流控样品池
:我们打算开发一种原位近红外光谱解决方案,用于监测芯片上器官装置微流控通道中的营养成分(如乳酸浓度)。在这项工作中,考虑到所提议的水溶液光谱方法的信噪比和灵敏度,对微量杯的几何形状、表面质量和结构的影响进行了表征和优化。使用这种特殊设计的微流控样品池的微体积近红外光谱仪方法的适用性已得到证实。
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