A multidisciplinary approach on music induced-analgesia differentiated by socio-cultural background in healthy volunteers (MOSART): A cross-over randomized controlled trial protocol

IF 1.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Contemporary Clinical Trials Communications Pub Date : 2024-06-01 DOI:10.1016/j.conctc.2024.101313
Antonia S. Becker , Emy S. van der Valk Bouman , Julian Schaap , Cecile C. de Vos , Koen van Eijck , Hans Jeekel , Markus Klimek
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引用次数: 0

Abstract

Background

Integrating music into pain treatment demonstrates significant benefits, effectively reducing subjective pain levels and perioperative opioid requirements. Currently, the relationship between the impact of specific types of music and listeners’ socio-cultural background is still unclear. This is especially relevant given that sociological research indicates that these factors can have a notable influence on music preference and perception. Current evidence suggests that individuals who choose their own music may experience greater benefits. However, additional research is needed to comprehensively grasp whether the effect of (preferred) music on pain endurance remains consistent across different socio-cultural backgrounds.

Methods

In this study, a collaborative effort between medical and sociological researchers aims to investigate music-induced analgesia differentiated by socio-cultural background in healthy volunteers. Participants (n = 84) will listen to self-, and researcher-chosen music and a podcast as a control condition in a cross-over study design. The primary outcome of this study is pain endurance measured by electric stimuli of increasing intensity. Detailed sociological validated questionnaires will be utilized. Considering the notable influence of educational level on music taste formation found in previous research and its crucial role as a source of socio-cultural differentiation, participants will be stratified based on their level of education.

Discussion

This experimental study represents one of the first efforts to gain a socio-culturally differentiated understanding of the therapeutic potential of music. Consequently, this could pave the way to purposefully and inclusively implement personalized music in healthcare settings.

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根据社会文化背景对健康志愿者进行音乐诱导镇痛的多学科方法(MOSART):交叉随机对照试验方案
背景将音乐融入疼痛治疗具有显著的益处,可有效降低主观疼痛程度和围手术期阿片类药物的需求量。目前,特定类型音乐的影响与听众的社会文化背景之间的关系仍不明确。社会学研究表明,这些因素会对音乐偏好和感知产生显著影响,因此这一点尤为重要。目前的证据表明,自己选择音乐的人可能会体验到更大的益处。本研究由医学研究人员和社会学研究人员合作进行,旨在调查音乐诱导镇痛在健康志愿者中的社会文化背景差异。参与者(n = 84)将在交叉研究设计中聆听自己和研究人员选择的音乐,并以播客作为对照条件。本研究的主要结果是通过强度不断增加的电刺激测量疼痛耐受力。将采用详细的社会学验证问卷。考虑到以往研究中发现的教育水平对音乐品味形成的显著影响,以及教育水平作为社会文化差异来源的关键作用,将根据受教育水平对参与者进行分层。因此,这可以为在医疗机构中有目的、有包容性地实施个性化音乐铺平道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
2.70
自引率
6.70%
发文量
146
审稿时长
20 weeks
期刊介绍: Contemporary Clinical Trials Communications is an international peer reviewed open access journal that publishes articles pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from a wide range of disciplines including medicine, life science, pharmaceutical science, biostatistics, epidemiology, computer science, management science, behavioral science, and bioethics. Contemporary Clinical Trials Communications is unique in that it is outside the confines of disease specifications, and it strives to increase the transparency of medical research and reduce publication bias by publishing scientifically valid original research findings irrespective of their perceived importance, significance or impact. Both randomized and non-randomized trials are within the scope of the Journal. Some common topics include trial design rationale and methods, operational methodologies and challenges, and positive and negative trial results. In addition to original research, the Journal also welcomes other types of communications including, but are not limited to, methodology reviews, perspectives and discussions. Through timely dissemination of advances in clinical trials, the goal of Contemporary Clinical Trials Communications is to serve as a platform to enhance the communication and collaboration within the global clinical trials community that ultimately advances this field of research for the benefit of patients.
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