Treatment Selection and Characteristics of Patients With Preiser Disease

Abstract

Purpose

Preiser disease is difficult to diagnose and treat because of its unclear pathophysiology. Although both nonsurgical treatment and surgical treatment for Preiser disease have been reported, there is no consensus on the optimal treatment because of its rarity. The purpose of this study was to investigate the relationship between treatment selection and characteristics of patients with Preiser disease.

Methods

This single-institution retrospective chart review included nine patients (two men and seven women) with Preiser disease who were treated at our hospital. We divided patients into two groups consisting of elderly (older than 65 years of age) and nonelderly patients. Herbert-Lanzetta classification, presence of dorsal intercalated segment instability (DISI), Watson classification based on plain radiography, Kalainov classification based on magnetic resonance imaging, and treatment modalities were investigated in both groups.

Results

In the elderly group, three of five cases were in advanced stages of Preiser disease according to the Herbert-Lanzetta classification. Three wrists had a DISI deformity. Three patients underwent conservative treatment. The two remaining cases classified as Herbert-Lanzetta stage II underwent closing radial wedge osteotomy. In the nonelderly group, three of four cases were in the early stages of Preiser disease according to the Herbert-Lanzetta classification. One wrist had a DISI deformity. Two patients were treated conservatively. The other two patients were surgically treated using closing radial wedge osteotomy in one case and vascularized bone graft from the second metacarpal base in another case, both classified as Herbert-Lanzetta stage II.

Conclusions

Most elderly patients with Preiser disease showed concurrent DISI at the time of initial presentation and advanced stage. Most elderly patients underwent nonsurgical treatment. Even when surgical treatment is implemented, our study suggests that the less invasive and optimal treatment is closing radial wedge osteotomy.

Type of study/level of evidence

Therapeutic IV.