Inter-individual responses to arginine oral supplementation on post-exercise hypotension in treated hypertensives: A pilot study

IF 0.8 4区 医学 Q4 SPORT SCIENCES Science & Sports Pub Date : 2024-06-01 DOI:10.1016/j.scispo.2023.01.009
J.V. Cavalari , A.F. Aguiar , J. Casonatto
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Abstract

Objective

To analyze the inter-individual responsiveness of post-exercise hypotension after a single dose of l-arginine supplementation in hypertensive patients.

Equipment and methods

A double-blind, randomized, placebo-controlled crossover trial was conducted. A total of 10 adults, hypertensive and sedentary, were randomly assigned to both experimental groups (placebo and l-arginine). The participants ingested a sachet containing 8 grams of l-arginine or placebo (corn starch). During the experimental sessions, individuals performed 40 min of walking/running on a treadmill at 60–70% of heart rate reserve. After the exercise sessions, blood pressure was measured every 10 min for 60 min.

Results

Considering systolic blood pressure, most participants responded favorably (lowering BP) in the “arginine” experimental arm.

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精氨酸口服补充剂对高血压患者运动后低血压的个体间反应:试点研究
目的分析高血压患者单剂量补充精氨酸后运动后低血压的个体间反应性。设备与方法进行了一项双盲、随机、安慰剂对照交叉试验。共有 10 名高血压和久坐不动的成年人被随机分配到两个实验组(安慰剂组和精氨酸组)。参与者摄入一小袋含有 8 克的精氨酸或安慰剂(玉米淀粉)。在实验过程中,参与者在跑步机上以 60-70% 的心率储备进行 40 分钟的步行/跑步。运动结束后,每 10 分钟测量一次血压,持续 60 分钟。结果考虑到收缩压,大多数参与者对 "精氨酸 "实验组反应良好(血压降低)。
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来源期刊
Science & Sports
Science & Sports 社会科学-运动科学
CiteScore
1.50
自引率
18.20%
发文量
143
审稿时长
19.7 weeks
期刊介绍: Science & Sports is a peer-reviewed journal, publishing worldwide high-quality and impactful papers of medical, scientific and applied technical research in the different fields of sports and physical activities: sport medicine, exercise physiology, sport physiology and performance, nutrition, traumatology relating to sport, rehabilitation or adapted physical activities. It facilitates the transfer of knowledge and technology between the clinic, research and practice in physical and athletic activity.
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