Integrated analysis of electroosmotic and magnetohydrodynamic peristaltic pumping in physiological systems: Implications for biomedical applications

Rajashekhar Choudhari, Dharmendra Tripathi, Hanumesh Vaidya, Kerehalli Vinayaka Prasad, Jyoti Shetty, Fateh Mebarek‐Oudina, Sami Ullah Khan, Katta Ramesh
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Abstract

The study of rheological properties in biological fluids, influenced by electroosmosis and magnetohydrodynamic (MHD) peristaltic mechanisms, plays a vital role in designing micro‐scale biomimetic pumping systems for targeted drug delivery. Considering these significant applications, the current study focuses on the integrated analysis of electroosmotic and magnetohydrodynamic peristaltic pumping of Williamson fluid within physiological systems with variable viscosity and thermal conductivity. The dimensional momentum equations are linearized under the approximation of lubrication theory. The current study deals with the impact of various physical parameters on flow, heat transfer, and pumping characteristics. These parameters include the magnetic parameter, variable viscosity, variable thermal conductivity, Helmholtz‐Smoluchowski velocity, and so on. It is noted from the current analysis that, Helmholtz‐Smoluchowski velocity and velocity slip parameters have decreasing effect on skin friction and Sherwood number. The electroosmotic and magnetic parameters contribute to larger trapped bolus sizes. These findings contribute significantly to advancing the development of efficient micro‐scale biomimetic pumping systems tailored for precise target drug delivery applications.
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综合分析生理系统中的电渗和磁流体蠕动泵:对生物医学应用的影响
生物流体的流变特性受电渗透和磁流体动力(MHD)蠕动机制的影响,研究生物流体的流变特性对设计微尺度生物仿生泵系统进行靶向药物输送起着至关重要的作用。考虑到这些重要应用,目前的研究重点是综合分析具有可变粘度和热导率的生理系统中 Williamson 流体的电渗和磁流体蠕动泵送。在润滑理论的近似条件下,尺寸动量方程被线性化。目前的研究涉及各种物理参数对流动、传热和泵送特性的影响。这些参数包括磁性参数、可变粘度、可变热导率、亥姆霍兹-斯莫卢霍夫斯基速度等。目前的分析表明,亥姆霍兹-斯莫卢霍夫斯基速度和速度滑移参数对皮肤摩擦和舍伍德数的影响是递减的。而电渗和磁参数则会导致更大的截留栓尺寸。这些发现极大地推动了高效微尺度仿生泵系统的发展,该系统专为精确靶向给药应用而量身定制。
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