Recyclization of 5-Aryl-1H-pyrrole-2,3-diones with Amidoximes. Synthesis of Enamines Containing a 1,2,4-Oxadiazole Fragment

IF 0.8 4区 化学 Q4 CHEMISTRY, ORGANIC Russian Journal of Organic Chemistry Pub Date : 2024-05-19 DOI:10.1134/S1070428024030023
D. I. Antonov, M. V. Dmitriev, I. A. Kuchumov, A. N. Maslivets
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Abstract

5-Aryl-1H-pyrrole-2,3-diones reacted with amidoximes to give enamines containing a 1,2,4-oxadi­azole fragment that are potential precursors to novel 1H-pyrrole-2,3-diones. The described reaction is the first example of recyclization of 4-unsubstitued 5-aryl-1H-pyrrole-2,3-diones by the action of 1,4-binucleophiles.

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5 芳基-1H-吡咯-2,3-二酮与脒肟的再环化。含 1,2,4-恶二唑片段的烯胺的合成
摘要 5-芳基-1H-吡咯-2,3-二酮与脒肟反应生成含有 1,2,4-噁二唑片段的烯胺,这些片段是新型 1H-吡咯-2,3-二酮的潜在前体。所述反应是 4-未取代的 5-芳基-1H-吡咯-2,3-二酮在 1,4-亲核物作用下发生再化学反应的第一个实例。
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来源期刊
CiteScore
1.40
自引率
25.00%
发文量
139
审稿时长
3-6 weeks
期刊介绍: Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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