New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications.

IF 1.7 4区医学 Q3 HEMATOLOGY International Journal of Hematology Pub Date : 2025-03-01 Epub Date: 2024-05-28 DOI:10.1007/s12185-024-03781-5

Kennosuke Karube, Akira Satou, Seiichi Kato

{"title":"New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications.","authors":"Kennosuke Karube, Akira Satou, Seiichi Kato","doi":"10.1007/s12185-024-03781-5","DOIUrl":null,"url":null,"abstract":"<p><p>In 2024, the World Health Organization (WHO) launched a new classification of lymphoid neoplasms, a revision of the previously used Revised 4th Edition of their classification (WHO-4R). However, this means that two classifications are now in simultaneous use: the 5th Edition of the WHO classification (WHO-5) and the International Consensus Classification (ICC). Instead of a comprehensive review of each disease entity, as already described elsewhere, this review focuses on revisions made in both the WHO-5 and ICC from WHO-4R and discrepancies between them regarding B-cell neoplasms. Similarities include cutaneous marginal zone lymphoma, cold agglutinin disease, non-primary effusion lymphoma-type effusion-based lymphoma, and gray zone lymphoma. Differences include plasma cell neoplasms, high-grade B-cell lymphoma (double hit lymphoma), follicular lymphoma, LPD with immune deficiency and dysregulation, extranodal large B-cell lymphoma, transformations of indolent B-cell lymphomas, and diffuse large B-cell lymphoma, not otherwise specified. Understanding the similarities and differences between the two latest classifications will aid daily diagnostic practice and future research on lymphoid neoplasms.</p>","PeriodicalId":13992,"journal":{"name":"International Journal of Hematology","volume":" ","pages":"331-341"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Hematology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12185-024-03781-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"HEMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

In 2024, the World Health Organization (WHO) launched a new classification of lymphoid neoplasms, a revision of the previously used Revised 4th Edition of their classification (WHO-4R). However, this means that two classifications are now in simultaneous use: the 5th Edition of the WHO classification (WHO-5) and the International Consensus Classification (ICC). Instead of a comprehensive review of each disease entity, as already described elsewhere, this review focuses on revisions made in both the WHO-5 and ICC from WHO-4R and discrepancies between them regarding B-cell neoplasms. Similarities include cutaneous marginal zone lymphoma, cold agglutinin disease, non-primary effusion lymphoma-type effusion-based lymphoma, and gray zone lymphoma. Differences include plasma cell neoplasms, high-grade B-cell lymphoma (double hit lymphoma), follicular lymphoma, LPD with immune deficiency and dysregulation, extranodal large B-cell lymphoma, transformations of indolent B-cell lymphomas, and diffuse large B-cell lymphoma, not otherwise specified. Understanding the similarities and differences between the two latest classifications will aid daily diagnostic practice and future research on lymphoid neoplasms.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

B 细胞肿瘤的新分类：第五次世界卫生组织分类与国际共识分类的比较。

2024 年，世界卫生组织（WHO）推出了新的淋巴肿瘤分类法，对之前使用的第四版修订版分类法（WHO-4R）进行了修订。然而，这意味着现在有两种分类法同时使用：第五版世界卫生组织分类法（WHO-5）和国际共识分类法（ICC）。本综述将重点讨论 WHO-5 和 ICC 对 WHO-4R 所做的修订，以及它们之间在 B 细胞肿瘤方面的差异，而不是对每种疾病实体进行全面综述。相似之处包括皮肤边缘区淋巴瘤、冷凝集素病、非原发性渗出淋巴瘤型渗出性淋巴瘤和灰区淋巴瘤。不同之处包括浆细胞瘤、高级别 B 细胞淋巴瘤（双击淋巴瘤）、滤泡淋巴瘤、伴有免疫缺陷和免疫调节失调的 LPD、结节外大 B 细胞淋巴瘤、懒散型 B 细胞淋巴瘤的转化以及弥漫性大 B 细胞淋巴瘤（未另作说明）。了解这两种最新分类的异同将有助于日常诊断实践和未来的淋巴肿瘤研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

International Journal of Hematology 医学-血液学

CiteScore

3.90

自引率

4.80%

发文量

223

审稿时长

6 months

期刊介绍： The International Journal of Hematology, the official journal of the Japanese Society of Hematology, has a long history of publishing leading research in hematology. The journal comprises articles that contribute to progress in research not only in basic hematology but also in clinical hematology, aiming to cover all aspects of this field, namely, erythrocytes, leukocytes and hematopoiesis, hemostasis, thrombosis and vascular biology, hematological malignancies, transplantation, and cell therapy. The expanded [Progress in Hematology] section integrates such relevant fields as the cell biology of stem cells and cancer cells, and clinical research in inflammation, cancer, and thrombosis. Reports on results of clinical trials are also included, thus contributing to the aim of fostering communication among researchers in the growing field of modern hematology. The journal provides the best of up-to-date information on modern hematology, presenting readers with high-impact, original work focusing on pivotal issues.