Should major trauma fractures be part of a fracture liaison service's remit: a cost-benefit estimate.

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Osteoporosis International Pub Date : 2024-08-01 Epub Date: 2024-05-27 DOI:10.1007/s00198-024-07134-0
D Chandrasoma, S Chiu, F Niddrie, G Major
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Abstract

The refracture rate after major trauma is approximately half (57%) the refracture rate after a minimal trauma injury. Extending Fracture Liaison Service activity to include major trauma patients creates significant additional direct cost, but remains essentially cost neutral if notional savings through refracture risk reduction are taken into account.

Purpose: To compare the 3-year refracture rate following minimal trauma (MT) and non-minimal trauma (non-MT) injuries and evaluate the cost of extending fracture liaison service (FLS) operations to non-MT presentations.

Methods: Patients aged 50, or above presenting to the John Hunter Hospital with a fracture in calendar year 2018 were identified through the Integrated Patient Management System (IPMS) of the Hunter New England Health Service's (HNEHS), and re-presentation to any HNEHS facility over the following 3 years monitored. The refracture rate of MT and non-MT presentations was compared and analysed using Cox proportional hazards regression models. The cost of including non-MT patients was estimated through the use of a previously conducted micro-costing analysis. The operational fidelity of the FLS to the previous estimate was confirmed by comparing the 3-year refracture rate of MT presentations in the two studies.

Results: The 3-year refracture rate following a MT injury was 8% and after non-MT injury 4.5%. Extension of FLS activities to include non-MT patients in 2022 would have cost an additional $198,326 AUD with a notional loss/saving of $ - 26,625/ + 26,913 AUD through refracture risk reduction. No clinically available characteristic at presentation predictive of increased refracture risk was identified.

Conclusion: The 3-year refracture after a non-MT injury is about half (57%) that of the refracture rate after a MT injury. Extending FLS activity to non-MT patients incurs a significant additional direct cost but remains cost neutral if notional savings gained through reduction in refracture risk are taken into account.

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重大创伤骨折是否应成为骨折联络服务的职责范围:成本效益估算。
重大创伤后的骨折率约为轻微创伤后骨折率的一半(57%)。将骨折联络服务活动扩展至重大创伤患者会产生大量额外的直接成本,但如果考虑到通过降低骨折风险而名义上节省的成本,则成本基本保持不变。目的:比较最小创伤(MT)和非最小创伤(non-MT)损伤后的3年骨折率,并评估将骨折联络服务(FLS)业务扩展至非MT病例的成本:通过亨特新英格兰卫生服务机构(HNEHS)的患者综合管理系统(IPMS),对2018日历年因骨折前往约翰-亨特医院就诊的50岁或以上患者进行识别,并对其在随后3年内再次前往任何HNEHS机构就诊的情况进行监测。使用 Cox 比例危险回归模型对 MT 和非 MT 患者的骨折率进行了比较和分析。通过之前进行的微观成本分析,对纳入非 MT 患者的成本进行了估算。通过比较两项研究中MT患者的3年骨折率,确认了FLS在操作上与之前的估算结果一致:结果:MT损伤后的3年再骨折率为8%,非MT损伤后为4.5%。如果在2022年将FLS活动扩展到非MT患者,将额外花费198,326澳元,通过降低骨折风险,名义损失/节省为-26,625澳元/ +26,913澳元。没有发现任何临床特征可预测骨折风险的增加:结论:非颅骨损伤后 3 年的骨折率约为颅骨损伤后骨折率的一半(57%)。将 FLS 活动扩展到非 MT 患者会产生大量额外的直接费用,但如果考虑到因降低骨折风险而在名义上节省的费用,则不会产生额外费用。
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来源期刊
Osteoporosis International
Osteoporosis International 医学-内分泌学与代谢
CiteScore
8.10
自引率
10.00%
发文量
224
审稿时长
3 months
期刊介绍: An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.
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