Analysis of the impact of health interventions on vaccination coverage for children under two years of age in municipalities of Minas Gerais.

Carolina Machado Moreira, Thales Philipe Rodrigues da Silva, Mariana Coelho De Almeida Neves, Marcus Vinicius Gonçalves da Cruz, Elice Eliane Nobre Ribeiro, Silvio Ferreira Júnior, Sheila Aparecida Ferreira Lachtim, Fernanda Penido Matozinhos
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Abstract

Objective: To evaluate the impact of the state action-research project on vaccination coverage in children under two years of age in the state of Minas Gerais, according to the size of the municipalities, comparing the years 2021 and 2022.

Methods: This is a study nested within the state action-research project, a before-after community clinical trial carried out in 212 municipalities in the state of Minas Gerais. This study used secondary data on Vaccination Coverage (VC), Homogeneity of Vaccines (HVC) and Abandonment rate of multi-dose vaccines. After classifying municipalities by size and vaccination coverage rates were equitably classified, an analysis of secondary data on 12 immunobiologicals indicated for the age group in question and their abandonment rate of multi-dose vaccines was carried out.

Results: There was an increase in the proportion of municipalities classified as small that reached the vaccination coverage target set by the National Immunization Program (PNI) after the action-research project was carried out. There was an increase in the proportion of small municipalities classified as having a low abandonment rate for the rotavirus vaccine, in the adequate homogeneity of vaccination coverage and in the classification of risk as very low risk and low and medium risk, all with a statistically significant difference.

Conclusion: There was an influence of municipal size on the effectiveness of the actions applied to increase vaccination coverage, explaining that proposing individualized actions for each municipality is essential to improve vaccination coverage.

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分析米纳斯吉拉斯州各市卫生干预措施对两岁以下儿童疫苗接种覆盖率的影响。
目的根据各市的规模,评估国家行动研究项目对米纳斯吉拉斯州两岁以下儿童疫苗接种覆盖率的影响,并对 2021 年和 2022 年进行比较:本研究是州行动研究项目中的一项嵌套研究,该项目是在米纳斯吉拉斯州 212 个市镇开展的一项前后对比的社区临床试验。本研究使用了有关疫苗接种覆盖率 (VC)、疫苗均匀性 (HVC) 和多剂量疫苗弃接率的二手数据。在对各市的规模和疫苗接种覆盖率进行公平分类后,对有关年龄组的 12 种免疫生物学指标及其多剂量疫苗放弃率的二手数据进行了分析:结果:开展行动研究项目后,达到国家免疫计划(PNI)规定的疫苗接种覆盖率目标的小城市比例有所增加。被归类为轮状病毒疫苗弃接种率低的小城市比例、疫苗接种覆盖率的充分均匀性以及将风险划分为极低风险、低风险和中等风险的比例都有所提高,所有这些在统计学上都有显著差异:结论:城市规模对提高疫苗接种覆盖率的行动效果有影响,这说明针对每个城市提出个性化行动对提高疫苗接种覆盖率至关重要。
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