Metabolic Dysfunction-associated Fatty Liver Disease: An Urgent Call for Global Action.

TouchREVIEWS in endocrinology Pub Date : 2024-04-01 Epub Date: 2023-11-08 DOI:10.17925/EE.2023.20.1.1
Cornelius J Fernandez, Lakshmi Nagendra, Joseph M Pappachan
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Abstract

There has been an exponential increase in the global prevalence of fatty liver disease in recent years in association with the obesity pandemic worldwide. 'Metabolic dysfunction-associated fatty liver disease', the new terminology adopted by an international panel of experts in 2020 to largely replace the old term 'non-alcoholic fatty liver disease', has now been accepted by most hepatologists and diabetologists across the globe. The term metabolic dysfunction-associated fatty liver disease was created to better reflect the metabolicand liver-specific manifestations and complications of fatty liver disease. It is important to disseminate our current understanding of this enigmatic disease among the global scientific fraternity. Recent publications, including articles from the latest issue of Endocrinology & Metabolism Clinics of North America, are attempting to fill this knowledge gap.

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代谢功能障碍相关性脂肪肝:全球行动的紧急呼吁》。
近年来,随着肥胖症在全球的流行,全球脂肪肝发病率呈指数级增长。代谢功能障碍相关性脂肪肝 "是一个国际专家小组于 2020 年采用的新术语,在很大程度上取代了旧术语 "非酒精性脂肪肝",现已被全球大多数肝病学家和糖尿病学家所接受。代谢功能障碍相关性脂肪肝这一术语的出现,更好地反映了脂肪肝的代谢和肝脏特异性表现及并发症。向全球科学界传播我们目前对这一神秘疾病的理解非常重要。最近的出版物,包括最新一期《北美内分泌与代谢临床》(Endocrinology & Metabolism Clinics of North America)上的文章,都在试图填补这一知识空白。
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