Treating Type 2 Diabetes With Early, Intensive, Multimodal Pharmacotherapy: Real-World Evidence From an International Collaborative Database

IF 3.6 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Journal of Diabetes Research Pub Date : 2024-05-30 DOI:10.1155/2024/3470654
Matthew Anson, Ayesha Malik, Sizheng S. Zhao, Philip Austin, Gema H. Ibarburu, Shabbar Jaffar, Anupam Garrib, Daniel J. Cuthbertson, Uazman Alam
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Abstract

Aims: We compared the glycaemic and cardiorenal effects of combination therapy involving metformin, pioglitazone, sodium-glucose-linked-cotransporter-2 inhibitor (SGLT2i), and glucagon-like peptide-1 receptor agonist (GLP-1RA) versus a more conventional glucocentric treatment approach combining sulphonylureas (SU) and insulin from the point of type 2 diabetes (T2D) diagnosis.
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用早期、强化、多模式药物疗法治疗 2 型糖尿病:来自国际合作数据库的真实世界证据
目的:我们比较了二甲双胍、吡格列酮、钠-葡萄糖链式转运体-2 抑制剂(SGLT2i)和胰高血糖素样肽-1 受体激动剂(GLP-1RA)联合疗法与从诊断为 2 型糖尿病(T2D)时起就采用的结合磺脲类药物(SU)和胰岛素的更传统的以糖为中心的治疗方法对血糖和心肾功能的影响。
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来源期刊
Journal of Diabetes Research
Journal of Diabetes Research ENDOCRINOLOGY & METABOLISM-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
8.40
自引率
2.30%
发文量
152
审稿时长
14 weeks
期刊介绍: Journal of Diabetes Research is a peer-reviewed, Open Access journal that publishes research articles, review articles, and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, etiology, pathogenesis, management, and prevention of diabetes, as well as associated complications, such as diabetic retinopathy, neuropathy and nephropathy.
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