Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints.

IF 4.3 2区医学 Current Osteoporosis Reports Pub Date : 2024-08-01 Epub Date: 2024-06-04 DOI:10.1007/s11914-024-00876-0

Jilmen Quintiens, G Harry van Lenthe

{"title":"Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints.","authors":"Jilmen Quintiens, G Harry van Lenthe","doi":"10.1007/s11914-024-00876-0","DOIUrl":null,"url":null,"abstract":"Purpose of review: Recently, photon-counting computed tomography (PCCT) has been introduced in clinical research and diagnostics. This review describes the technological advances and provides an overview of recent applications with a focus on imaging of bone.Recent findings: PCCT is a full-body scanner with short scanning times that provides better spatial and spectral resolution than conventional energy-integrating-detector CT (EID-CT), along with an up to 50% reduced radiation dose. It can be used to quantify bone mineral density, to perform bone microstructural analyses and to assess cartilage quality with adequate precision and accuracy. Using a virtual monoenergetic image reconstruction, metal artefacts can be greatly reduced when imaging bone-implant interfaces. Current PCCT systems do not allow spectral imaging in ultra-high-resolution (UHR) mode. Given its improved resolution, reduced noise and spectral imaging capabilities PCCT has diagnostic capacities in both qualitative and quantitative imaging that outperform those of conventional CT. Clinical use in monitoring bone health has already been demonstrated. The full potential of PCCT systems will be unlocked when UHR spectral imaging becomes available.","PeriodicalId":48750,"journal":{"name":"Current Osteoporosis Reports","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Osteoporosis Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11914-024-00876-0","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/4 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Recently, photon-counting computed tomography (PCCT) has been introduced in clinical research and diagnostics. This review describes the technological advances and provides an overview of recent applications with a focus on imaging of bone.

Recent findings: PCCT is a full-body scanner with short scanning times that provides better spatial and spectral resolution than conventional energy-integrating-detector CT (EID-CT), along with an up to 50% reduced radiation dose. It can be used to quantify bone mineral density, to perform bone microstructural analyses and to assess cartilage quality with adequate precision and accuracy. Using a virtual monoenergetic image reconstruction, metal artefacts can be greatly reduced when imaging bone-implant interfaces. Current PCCT systems do not allow spectral imaging in ultra-high-resolution (UHR) mode. Given its improved resolution, reduced noise and spectral imaging capabilities PCCT has diagnostic capacities in both qualitative and quantitative imaging that outperform those of conventional CT. Clinical use in monitoring bone health has already been demonstrated. The full potential of PCCT systems will be unlocked when UHR spectral imaging becomes available.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

用于骨骼和关节微结构成像的光子计数计算机断层扫描。

综述目的：最近，光子计数计算机断层扫描（PCCT）被引入临床研究和诊断领域。这篇综述介绍了该技术的进展，并概述了最近的应用，重点是骨骼成像：PCCT 是一种扫描时间短的全身扫描仪，与传统的能量积分探测器 CT（EID-CT）相比，它能提供更好的空间和光谱分辨率，同时辐射剂量最多可减少 50%。它可用于量化骨矿物质密度，进行骨微结构分析，并以足够的精度和准确性评估软骨质量。利用虚拟单能图像重建技术，在对骨-种植体界面进行成像时，可以大大减少金属伪影。目前的 PCCT 系统无法在超高分辨率（UHR）模式下进行光谱成像。鉴于 PCCT 具有更高的分辨率、更低的噪声和光谱成像能力，其定性和定量成像诊断能力均优于传统 CT。在监测骨骼健康方面的临床应用已得到证实。当 UHR 光谱成像可用时，PCCT 系统的全部潜力将被释放出来。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Osteoporosis Reports ENDOCRINOLOGY & METABOLISM-

CiteScore

8.40

自引率

2.30%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of osteoporosis. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as current and future therapeutics, epidemiology and pathophysiology, and evaluation and management. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.

期刊最新文献

Adiposity and Mineral Balance in Chronic Kidney Disease. Between a Rock and a Short Place-The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan. Vitamin D-Do Diet Recommendations for Health Remain Strong? Correction: Bringing Mechanical Context to Image-Based Measurements of Bone Integrity. Practical Compass of Single-Cell RNA-Seq Analysis.