A sex- and gender-based analysis of alcohol treatment intervention research involving youth: A methodological systematic review.

IF 15.8 1区 医学 Q1 Medicine PLoS Medicine Pub Date : 2024-06-03 eCollection Date: 2024-06-01 DOI:10.1371/journal.pmed.1004413
A J Lowik, Caroline Mniszak, Michelle Pang, Kimia Ziafat, Mohammad Karamouzian, Rod Knight
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引用次数: 0

Abstract

Background: While there is widespread consensus that sex- and gender-related factors are important for how interventions are designed, implemented, and evaluated, it is not currently known how alcohol treatment research accounts for sex characteristics and/or gender identities and modalities. This methodological systematic review documents and assesses how sex characteristics, gender identities, and gender modalities are operationalized in alcohol treatment intervention research involving youth.

Methods and findings: We searched MEDLINE, Embase, Cochrane Central Registry of Controlled Trials, PsycINFO, CINAHL, LGBT Life, Google Scholar, Web of Science, and grey literature from 2008 to 2023. We included articles that reported genders and/or sexes of participants 30 years of age and under and screened participants using AUDIT, AUDIT-C, or a structured interview using DSM-IV criteria. We limited the inclusion to studies that enrolled participants in alcohol treatment interventions and used a quantitative study design. We provide a narrative overview of the findings. Of 8,019 studies screened for inclusion, 86 articles were included in the review. None of the studies defined, measured, and reported both sex and gender variables accurately. Only 2 studies reported including trans participants. Most of the studies used gender or sex measures as a covariate to control for the effects of sex or gender on the intervention but did not discuss the rationale for or implications of this procedure.

Conclusions: Our findings identify that the majority of alcohol treatment intervention research with youth conflate sex and gender factors, including terminologically, conceptually, and methodologically. Based on these findings, we recommend future research in this area define and account for a spectrum of gender modalities, identities, and/or sex characteristics throughout the research life cycle, including during study design, data collection, data analysis, and reporting. It is also imperative that sex and gender variables are used expansively to ensure that intersex and trans youth are meaningfully integrated.

Trial registration: Registration: PROSPERO, registration number: CRD42019119408.

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对涉及青少年的酒精治疗干预研究进行基于性别的分析:方法论系统回顾。
背景:尽管人们普遍认为与性和性别相关的因素对于干预措施的设计、实施和评估非常重要,但目前还不清楚酒精治疗研究是如何考虑性别特征和/或性别认同和模式的。本方法论系统性综述记录并评估了在涉及青少年的酒精治疗干预研究中如何操作性特征、性别认同和性别模式:我们检索了 2008 年至 2023 年间的 MEDLINE、Embase、Cochrane Central Registry of Controlled Trials、PsycINFO、CINAHL、LGBT Life、Google Scholar、Web of Science 和灰色文献。我们收录了那些报告了 30 岁及以下参与者的性别,并使用 AUDIT、AUDIT-C 或使用 DSM-IV 标准的结构化访谈对参与者进行筛查的文章。我们仅限于纳入酒精治疗干预并采用定量研究设计的研究。我们对研究结果进行了叙述性概述。在筛选出的 8,019 项研究中,有 86 篇文章被纳入综述。这些研究均未准确定义、测量和报告性与性别变量。只有 2 项研究报告了变性参与者。大多数研究使用性别或性测量作为协变量来控制性或性别对干预的影响,但没有讨论这一程序的原理或影响:我们的研究结果表明,大多数针对青少年的酒精治疗干预研究都混淆了性和性别因素,包括术语、概念和方法上的混淆。基于这些发现,我们建议今后在这一领域的研究在整个研究生命周期中,包括在研究设计、数据收集、数据分析和报告过程中,对各种性别模式、身份和/或性别特征进行定义和说明。此外,还必须广泛使用性和性别变量,以确保将双性青年和变性青年有意义地纳入其中:注册:注册:PROSPERO,注册号:CRD42019119408:CRD42019119408。
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来源期刊
PLoS Medicine
PLoS Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
17.60
自引率
0.60%
发文量
227
审稿时长
4-8 weeks
期刊介绍: PLOS Medicine is a prominent platform for discussing and researching global health challenges. The journal covers a wide range of topics, including biomedical, environmental, social, and political factors affecting health. It prioritizes articles that contribute to clinical practice, health policy, or a better understanding of pathophysiology, ultimately aiming to improve health outcomes across different settings. The journal is unwavering in its commitment to uphold the highest ethical standards in medical publishing. This includes actively managing and disclosing any conflicts of interest related to reporting, reviewing, and publishing. PLOS Medicine promotes transparency in the entire review and publication process. The journal also encourages data sharing and encourages the reuse of published work. Additionally, authors retain copyright for their work, and the publication is made accessible through Open Access with no restrictions on availability and dissemination. PLOS Medicine takes measures to avoid conflicts of interest associated with advertising drugs and medical devices or engaging in the exclusive sale of reprints.
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