Colorectal cancer: Getting the perspective and context right.

IF 2.6 Q3 ONCOLOGY World journal of clinical oncology Pub Date : 2024-05-24 DOI:10.5306/wjco.v15.i5.599
Jun De Lu, Kok Yang Tan
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Abstract

Colorectal cancer (CRC) is a significant global health burden, being the third leading cancer globally. Its incidence has been observed to be higher in developed regions such as North America and Europe with geographical variations in mortality rates. Efforts to address this disease burden include promoting early detection through screening and implementing treatment strategies to improve patient outcomes. With the growing and aging population, the incidence of CRC will undoubtedly increase. These epidemiological trends will mean that healthcare professionals will increasingly encounter CRC in more complex patients. Hence, it becomes imperative to have a deeper appreciation of the pathophysiology of CRC and understand the intricate interplay between a patient's physiology and their goals of care before offering treatment. This review article will aim to encapsulate the important nuances and perspectives of managing this disease in the context of an elderly patient.

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大肠癌:正确的视角和背景。
结肠直肠癌(CRC)是全球第三大癌症,对全球健康造成重大负担。据观察,北美和欧洲等发达地区的发病率较高,死亡率也存在地域差异。为解决这一疾病负担所做的努力包括通过筛查促进早期发现,以及实施治疗策略以改善患者预后。随着人口的增长和老龄化,CRC 的发病率无疑会增加。这些流行病学趋势意味着医护人员将越来越多地在更复杂的患者中遇到 CRC。因此,在提供治疗之前,必须深入了解 CRC 的病理生理学,并理解患者的生理状况与治疗目标之间错综复杂的相互作用。这篇综述文章将从老年患者的角度出发,概括管理这种疾病的重要细微差别和视角。
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期刊介绍: The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.
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