Gerhard van Wyk, Liezel Coetzee, Mogamat-Yazied Chothia
{"title":"Acute kidney injury in an HIV patient with plasmablastic lymphoma - A double-edged sword.","authors":"Gerhard van Wyk, Liezel Coetzee, Mogamat-Yazied Chothia","doi":"10.4102/sajid.v39i1.637","DOIUrl":null,"url":null,"abstract":"<p><p>HIV patients frequently develop acute kidney injury (AKI) because of sepsis and diarrhoeal disease. Here, we report a case of an HIV-positive man with partially treated sinonasal plasmablastic lymphoma (PBL) and unexplained AKI. A kidney biopsy revealed two pathological processes.</p><p><strong>Contribution: </strong>While urinary tract obstruction is the most common mechanism by which PBL causes AKI, maintaining a high level of suspicion for multiple pathological processes in cases involving light chain producing PBL.</p>","PeriodicalId":44007,"journal":{"name":"Southern African Journal of Infectious Diseases","volume":"39 1","pages":"637"},"PeriodicalIF":1.4000,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151415/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Southern African Journal of Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4102/sajid.v39i1.637","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
HIV patients frequently develop acute kidney injury (AKI) because of sepsis and diarrhoeal disease. Here, we report a case of an HIV-positive man with partially treated sinonasal plasmablastic lymphoma (PBL) and unexplained AKI. A kidney biopsy revealed two pathological processes.
Contribution: While urinary tract obstruction is the most common mechanism by which PBL causes AKI, maintaining a high level of suspicion for multiple pathological processes in cases involving light chain producing PBL.
由于败血症和腹泻病,艾滋病患者经常会出现急性肾损伤(AKI)。在此,我们报告了一例 HIV 阳性男性患者,他患有部分治疗的鼻窦浆细胞性淋巴瘤(PBL)和不明原因的急性肾损伤。肾活检发现了两种病理过程:贡献:虽然尿路梗阻是PBL导致AKI的最常见机制,但在涉及产生轻链的PBL的病例中,应高度怀疑多种病理过程。