Artificial Intelligence in Eye Movements Analysis for Alzheimer's Disease Early Diagnosis.

Shadi Farabi Maleki, Milad Yousefi, Navid Sobhi, Ali Jafarizadeh, Roohallah Alizadehsani, Juan Manuel Gorriz-Saez
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Abstract

As the world's population ages, Alzheimer's disease is currently the seventh most common cause of death globally; the burden is anticipated to increase, especially among middle-class and elderly persons. Artificial intelligence-based algorithms that work well in hospital environments can be used to identify Alzheimer's disease. A number of databases were searched for English- language articles published up until March 1, 2024, that examined the relationships between artificial intelligence techniques, eye movements, and Alzheimer's disease. A novel non-invasive method called eye movement analysis may be able to reflect cognitive processes and identify anomalies in Alzheimer's disease. Artificial intelligence, particularly deep learning, and machine learning, is required to enhance Alzheimer's disease detection using eye movement data. One sort of deep learning technique that shows promise is convolutional neural networks, which need further data for precise classification. Nonetheless, machine learning models showed a high degree of accuracy in this context. Artificial intelligence-driven eye movement analysis holds promise for enhancing clinical evaluations, enabling tailored treatment, and fostering the development of early and precise Alzheimer's disease diagnosis. A combination of artificial intelligence-based systems and eye movement analysis can provide a window for early and non-invasive diagnosis of Alzheimer's disease. Despite ongoing difficulties with early Alzheimer's disease detection, this presents a novel strategy that may have consequences for clinical evaluations and customized medication to improve early and accurate diagnosis.

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用于阿尔茨海默病早期诊断的人工智能眼动分析。
随着世界人口的老龄化,阿尔茨海默病目前已成为全球第七大常见死因;预计这一负担还将加重,尤其是在中产阶级和老年人中。基于人工智能的算法在医院环境中运行良好,可用于识别阿尔茨海默病。我们在多个数据库中搜索了截至2024年3月1日发表的研究人工智能技术、眼球运动和阿尔茨海默病之间关系的英文文章。一种名为眼动分析的新型非侵入性方法或许能够反映阿尔茨海默病的认知过程并识别异常。要利用眼动数据加强阿尔茨海默病的检测,需要人工智能,特别是深度学习和机器学习。卷积神经网络是一种前景看好的深度学习技术,它需要更多数据才能进行精确分类。尽管如此,机器学习模型在这方面还是表现出了很高的准确性。人工智能驱动的眼球运动分析有望加强临床评估,实现有针对性的治疗,并促进阿尔茨海默病早期精确诊断的发展。基于人工智能的系统与眼动分析相结合,可以为阿尔茨海默病的早期无创诊断提供一个窗口。尽管阿尔茨海默病的早期检测一直存在困难,但这一新策略可能会对临床评估和定制药物治疗产生影响,从而提高早期诊断的准确性。
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