Primary Cutaneous Cryptococcosis in an Elderly Patient: A Case Report and Review of Literature.

IF 1.1 4区 医学 Q4 DERMATOLOGY American Journal of Dermatopathology Pub Date : 2024-08-01 Epub Date: 2024-06-06 DOI:10.1097/DAD.0000000000002758
Yuyan Zhang, Faxing Jiang, Siping Zhang, Jinli Liu
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Abstract

Abstract: This article reports an elderly male patient with nodules and ulcers on the face and behind the left ear after trauma. Primary cutaneous cryptococcosis was confirmed using pathological biopsy, special staining, tissue culture, and fungal sequencing. The patient received a therapeutic intervention involving the administration of the antifungal agent itraconazole. Substantial amelioration of cutaneous manifestations was observed after a 3-month course of treatment. After an elapsed interval, the patient was diagnosed with esophageal tumor. Moreover, the literature on 33 patients with primary cutaneous cryptococcosis published in the past 10 years was also reviewed.

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老年患者的原发性皮肤隐球菌病:病例报告与文献综述。
摘要:本文报告了一名老年男性患者的病例,他在外伤后面部和左耳后出现结节和溃疡。通过病理活检、特殊染色、组织培养和真菌测序证实了原发性皮肤隐球菌病。患者接受了抗真菌药物伊曲康唑的治疗干预。经过 3 个月的治疗,患者的皮肤症状明显好转。经过一段时间的治疗后,患者被诊断为食道肿瘤。此外,我们还查阅了过去 10 年中发表的 33 例原发性皮肤隐球菌病患者的文献。
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来源期刊
CiteScore
1.80
自引率
9.10%
发文量
453
审稿时长
3 months
期刊介绍: The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians
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