Stackable Medical-Grade Skincare for the Cosmetic Medicine Patient: A Long-Term Pilot Assessment.

Aesthetic surgery journal. Open forum Pub Date : 2024-06-05 eCollection Date: 2024-01-01 DOI:10.1093/asjof/ojae037
Sydney Pryor, Alec Semersky, Tiffany Sabev, Julius Few
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Abstract

Background: Multiple intrinsic and extrinsic factors influence aging and lead to visible changes in the skin, including dryness, fine lines and wrinkles, loss of elasticity, surface roughness, uneven pigmentation, and loss of luminosity. Although it is well established that a single combination of topicals can address multiple signs of skin aging, it is common for patients' at-home skin treatment routines to include multiple different topicals with different active ingredients. The layering of active ingredients can cause skin irritation, and lead to noncompliance with a consistent routine. Further, multiple active ingredients may exacerbate irritation from in-office aesthetic treatments.

Objectives: To assess the long-term efficacy, safety, tolerability, and patient adherence to a Stackable Treatment topical routine consisting of 4 complementary topical formulations.

Methods: This study examined a daily topical routine (Stackable Treatment routine) consisting of 4 topical formulas with different active ingredients, and evaluated the routine's safety, tolerability, and efficacy in a composite of in-office treatment patients who applied the routine for a minimum of 1 year.

Results: Of the 14 patients, 0 experienced adverse reactions. Improvements to multiple skin parameters were observed, including improvements to skin hydration, surface texture, pigmentation, vasculature, and the appearance of scars. The majority of patients continue to use the Stackable Treatment routine after the study's conclusion.

Conclusions: The combination of low incidence of irritation, high patient satisfaction, and overall efficacy of the routine indicates the Stackable Treatment routine may be well suited as a foundational skin care regimen that can complement in-office aesthetic treatments.

Level of evidence 4:

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针对美容医学患者的可叠加医疗级护肤品:长期试点评估
背景:多种内在和外在因素影响着皮肤的老化,并导致皮肤发生明显变化,包括干燥、细纹和皱纹、失去弹性、表面粗糙、色素不均和失去光泽。虽然单一的外用药组合可以解决多种皮肤老化迹象,但患者的家庭皮肤护理程序通常包括多种不同活性成分的外用药。活性成分的层层叠加可能会对皮肤造成刺激,并导致患者不遵守一致的日常护理程序。此外,多种活性成分可能会加剧诊室美容治疗的刺激性:评估由 4 种互补外用制剂组成的可叠加治疗外用程序的长期疗效、安全性、耐受性和患者依从性:本研究考察了由 4 种不同活性成分的外用配方组成的日常外用常规疗法(可叠加治疗常规疗法),并对使用该常规疗法至少 1 年的诊室治疗患者的安全性、耐受性和疗效进行了综合评估:结果:14 名患者中,0 人出现不良反应。多种皮肤参数都得到了改善,包括皮肤水合度、表面质地、色素沉着、血管和疤痕外观。研究结束后,大多数患者仍在继续使用堆栈式护理程序:结论:刺激发生率低、患者满意度高、疗程总体疗效好,这些综合因素表明,可叠加护理疗程非常适合作为基础皮肤护理疗程,可作为诊室美容治疗的补充:
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