A dermoscopy case series of cutaneous metastases from breast cancer in Filipino females

Rouslia Q. Alfaro, Arunee H. Siripunvarapon, Maria F. S. Quinio, Celine M. H. Duran, Joanne R. Pamin, Claire M. R. Habito
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Abstract

There is a limited number of dermoscopic images of cutaneous metastases from breast cancer. We report three cases of cutaneous metastases in Filipino females with breast cancer. They were referred to the Dermatology outpatient clinic with round, firm, nontender, erythematous nodules on the chest and trunk. Dermoscopic findings noted were linear, irregular, arborizing and polymorphic vessels, bright white lines at the periphery and white areas, homogenous yellow to yellow‐orange structureless areas with linear fissure‐like structures and irregular diffuse blue‐black pigmentation, multiple brown dots and globules, and pink homogeneous areas. The clinical presentation, dermoscopy, histopathology and immunohistochemistry findings were consistent with cutaneous metastases from breast cancer. Familiarity and knowledge of dermoscopic patterns will improve diagnostic accuracy and early recognition of cutaneous metastases.
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菲律宾女性乳腺癌皮肤转移的皮肤镜病例系列
有关乳腺癌皮肤转移的皮肤镜图像数量有限。我们报告了三例菲律宾女性乳腺癌皮肤转移病例。她们因胸部和躯干出现圆形、坚实、无触痛的红斑结节而被转诊至皮肤科门诊。皮肤镜检查结果为线状、不规则、树枝状和多形性血管,周边和白色区域有明亮的白线,同质的黄色至黄橙色无结构区域有线状裂隙样结构和不规则的弥漫性蓝黑色色素沉着,多个棕色小点和球状物,以及粉红色同质区域。临床表现、皮肤镜检查、组织病理学和免疫组化检查结果与乳腺癌皮肤转移一致。熟悉和了解皮肤镜模式将提高诊断的准确性,并能及早识别皮肤转移瘤。
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