Test the effectiveness of some medications and vitamin D3 used against COVID-19 on Gram-positive and Gram-negative bacteria isolated from people infected with the Coronavirus

Amal F. Al-Gorani, Hanan Saadon, Ahmed. K. Ajeel, Noor Abd alkhudhur Salman, Aya Talib Jawad, Hussein Adnan Obaid, Hasan Mohsen Koti
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Abstract

The COVID-19 pandemic has led to a search for effective pharmaceuticals and vitamins to combat the virus. These therapies have antiviral capabilities and can affect both gram-negative and gram-positive bacteria. This study aims to assess the effectiveness of various medications and nutrients in treating bacterial infections linked to COVID-19. In vitro, tests will be conducted to evaluate these therapies' antibacterial efficacy against both gram-negative and gram-positive bacteria. In the current study, we test a group of antibiotics commonly used in treating Coronavirus on different types of Gram-positive and Gram-negative bacteria. They found that Azithromycin was highly effective against both positive and negative bacteria, but its effectiveness decreased when combined with vitamin D. Levofloxacin was the most effective antibiotic, and its efficacy was not affected by the addition of zinc or vitamin D. Acyclovir had a slight effect on bacteria when used alone, but its efficacy improved with zinc. Zinc and Vitamin D had a high degree of effectiveness, but Vitamin D had relatively low efficacy, except against one type of bacteria. The study aims to evaluate the effectiveness of drugs and vitamins against bacterial infections in COVID-19 patients. The results will provide a better understanding of the potential advantages of these medications in controlling bacterial infections. (The abstract should have one paragraph) The study aims to evaluate the effectiveness of drugs and vitamins against bacterial infections in COVID-19 patients. The results will provide a better understanding of the potential advantages of these medications in controlling bacterial infections.
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测试某些抗 COVID-19 的药物和维生素 D3 对从感染冠状病毒的人群中分离出的革兰氏阳性和革兰氏阴性细菌的效果
COVID-19 大流行促使人们寻找有效的药物和维生素来对抗病毒。这些疗法具有抗病毒能力,并能影响革兰氏阴性菌和革兰氏阳性菌。这项研究旨在评估各种药物和营养素在治疗与 COVID-19 相关的细菌感染方面的有效性。我们将在体外进行测试,评估这些疗法对革兰氏阴性菌和革兰氏阳性菌的抗菌效果。在目前的研究中,我们测试了一组常用于治疗冠状病毒的抗生素对不同类型革兰氏阳性菌和革兰氏阴性菌的抗菌效果。他们发现,阿奇霉素对阳性和阴性细菌都非常有效,但与维生素 D 合用时,其疗效会下降。左氧氟沙星是最有效的抗生素,其疗效不受锌或维生素 D 的影响。锌和维生素 D 的疗效较高,但维生素 D 的疗效相对较低,只有对一种细菌的疗效除外。该研究旨在评估药物和维生素对 COVID-19 患者细菌感染的疗效。研究旨在评估药物和维生素对 COVID-19 患者细菌感染的疗效,研究结果将有助于更好地了解这些药物在控制细菌感染方面的潜在优势。(摘要应有一段话)该研究旨在评估药物和维生素对 COVID-19 患者细菌感染的疗效。研究结果将使人们更好地了解这些药物在控制细菌感染方面的潜在优势。
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