Combined nutritional status and activities of daily living disability is associated with one-year mortality after hip fracture surgery for geriatric patients: a retrospective cohort study.

IF 3.4 3区 医学 Q2 GERIATRICS & GERONTOLOGY Aging Clinical and Experimental Research Pub Date : 2024-06-08 DOI:10.1007/s40520-024-02786-8
Ying Chen, Ying Guo, Gang Tong, Yu He, Ruihua Zhang, Qi Liu
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Abstract

Objective: We aimed to explore the association combined nutritional status and activities of daily living disability with all-cause mortality of older adults with hip fracture in the first year after hospitalization.

Methods: This is a single-center retrospective cohort study in older adults with hip fracture patients. Clinical data and laboratory results were collected from electronic medical record system of our hospital (2014-2021). The endpoint of this study was all-cause mortality in the first year after hospitalization.

Results: A total of 303 older adults were enrolled and all-cause mortality was 21.8%. The study population was categorized by CONUT score. Patients in CONUT score 5-12 had a higher age, ASA status, CRP and creatinine level, more patients with history of fracture, pneumonia and delirium, meanwhile, lower BMI and ADL score, lower hemoglobin, lymphocyte, total protein, albumin, triglyceride, total cholesterol and one year survival than those in CONUT score 0-4 (all P < 0.05). Multivariable Cox analysis showed that BMI, ADL score and CONUT score were independent risk factors for all-cause mortality of hip fracture in older adults (HR (95% CI):2.808(1.638, 4.814), P < 0.001; 2.862(1.637, 5.003), P < 0.001; 2.322(1.236, 4.359), P = 0.009, respectively). More importantly, the combined index of CONUT and ADL score had the best predictive performance based on ROC curve (AUC 0.785, 95% CI: 0.734-0.830, P < 0.0001). Kaplan-Meier survival curves for all-cause mortality showed that patients with CONUT score increase and ADL score impairment had a higher mortality rate at 1 year compared to CONUT score decrease and ADL score well (Log Rank χ2 = 45.717, P < 0.0001).

Conclusions: Combined CONUT and ADL score is associated with one-year mortality after hip fracture surgery for geriatric patients.

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老年患者髋部骨折术后一年死亡率与营养状况和日常生活能力障碍的综合关系:一项回顾性队列研究。
目的我们旨在探讨髋部骨折老年人住院后第一年内营养状况和日常生活活动障碍与全因死亡率之间的关系:这是一项针对老年髋部骨折患者的单中心回顾性队列研究。临床数据和实验室结果来自本院的电子病历系统(2014-2021 年)。研究终点为住院后第一年的全因死亡率:共有 303 名老年人参与研究,全因死亡率为 21.8%。研究对象按 CONUT 评分进行分类。与 CONUT 评分 0-4 的患者相比,CONUT 评分 5-12 的患者年龄、ASA 状况、CRP 和肌酐水平更高,有骨折、肺炎和谵妄病史的患者更多,同时,BMI 和 ADL 评分更低,血红蛋白、淋巴细胞、总蛋白、白蛋白、甘油三酯、总胆固醇和一年存活率更低(均为 P 结论:CONUT 评分 5-12 的患者年龄、ASA 状况、CRP 和肌酐水平更高,有骨折、肺炎和谵妄病史的患者更多,同时,BMI 和 ADL 评分更低:CONUT和ADL综合评分与老年患者髋部骨折术后一年的死亡率有关。
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来源期刊
CiteScore
7.90
自引率
5.00%
发文量
283
审稿时长
1 months
期刊介绍: Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.
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