The aMPPle differentiation potential of TH2 cells in human allergy

IF 17.6 1区 医学 Q1 IMMUNOLOGY Science Immunology Pub Date : 2024-06-07 DOI:10.1126/sciimmunol.adq7287
Sindhura Siddapureddy, Stephanie Eisenbarth
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Abstract

Single-cell studies of human tissues reveal a stem-like TH2 subset as progenitors of key effectors in chronic type 2 inflammation.
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人类过敏症中 TH2 细胞的分化潜能。
对人体组织的单细胞研究显示,在慢性 2 型炎症中,干样 TH2 亚群是关键效应因子的祖先。
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来源期刊
Science Immunology
Science Immunology Immunology and Microbiology-Immunology
CiteScore
32.90
自引率
2.00%
发文量
183
期刊介绍: Science Immunology is a peer-reviewed journal that publishes original research articles in the field of immunology. The journal encourages the submission of research findings from all areas of immunology, including studies on innate and adaptive immunity, immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology. Additionally, the journal covers research on immune contributions to health and disease, such as host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency. Science Immunology maintains the same high-quality standard as other journals in the Science family and aims to facilitate understanding of the immune system by showcasing innovative advances in immunology research from all organisms and model systems, including humans.
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