Two challenging cases of anti-MDA-5 dermatomyositis with rapidly progressive interstitial lung disease.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Oxford Medical Case Reports Pub Date : 2024-06-07 eCollection Date: 2024-06-01 DOI:10.1093/omcr/omae061
Kathryn Biddle, Elif Agaoglu, Geoffrey Brent, John Adam, Rachel Nockels, Adam Loveridge, Farid Bazari, Janakan Natkunarajah, Israa Al-Shakarchi
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Abstract

Anti-MDA-5 dermatomyositis (DM) is a subtype of idiopathic inflammatory myopathy, commonly presenting as clinically amyopathic dermatomyositis. It is associated with rapidly progressive interstitial lung disease and a poor prognosis. Here, we present two cases of anti-MDA-5 DM and discuss the challenges associated with timely diagnosis, and the importance of early and aggressive treatment.

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两例具有挑战性的抗MDA-5皮肌炎伴快速进展性间质性肺病病例。
抗MDA-5皮肌炎(DM)是特发性炎症性肌病的一种亚型,临床上通常表现为肌病性皮肌炎。它与快速进展的间质性肺病和不良预后有关。在此,我们将介绍两例抗MDA-5 DM病例,并讨论与及时诊断相关的挑战以及早期积极治疗的重要性。
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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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