The sensitivity of MIPs of 3D contrast-enhanced VIBE T1-weighted imaging for the detection of small brain metastases (≤ 5 mm) on 1.5 tesla MRI.

IF 1.3 Q4 NEUROIMAGING Neuroradiology Journal Pub Date : 2024-12-01 Epub Date: 2024-06-11 DOI:10.1177/19714009241260802

Marco Parillo, Daniele Vertulli, Federica Vaccarino, Carlo Augusto Mallio, Bruno Beomonte Zobel, Carlo Cosimo Quattrocchi

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引用次数: 0

Abstract

Objectives: To evaluate whether the use of Maximum Intensity Projection (MIP) images derived from contrast-enhanced 3D-T1-weighted volumetric interpolated breath-hold examination (VIBE) would allow more sensitive detection of small (≤5 mm) brain metastases (BM) compared with source as well as 2D-T1-weighted spin-echo (SE) images.

Methods: We performed a single center retrospective study on subjects with BM who underwent 1.5 tesla brain magnetic resonance imaging. Two readers counted the number of small BM for each of the seven sets of contrast-enhanced images created: axial 2D-T1-weighted SE, 3D-T1-weighted VIBE, 2.5 mm-thick-MIP T1-weighted VIBE, and 5 mm-thick-MIP T1-weighted VIBE; sagittal 3D-T1-weighted VIBE, 2.5 mm-thick-MIP T1-weighted VIBE, and 5 mm-thick-MIP T1-weighted VIBE. Total number of lesions detected on each image type was compared. Sensitivity, the average rates of false negatives and false positives, and the mean discrepancy were evaluated.

Results: A total of 403 small BM were identified in 49 patients. Significant differences were found: in the number of true positives and false negatives between the axial 2D-T1-weighted SE sequence and all other imaging techniques; in the number of false positives between the axial 2D-T1-weighted SE and the axial 3D-T1-weighted VIBE sequences. The two image types that combined offered the highest sensitivity were 2D-T1-weighted SE and axial 2.5 mm-thick-MIP T1-weighted VIBE. The axial 2D-T1-weighted SE sequence differed significantly in sensitivity from all other sequences.

Conclusion: MIP images did not show a significant difference in sensitivity for the detection of small BM compared with native images.

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三维对比增强 VIBE T1 加权成像的 MIPs 对 1.5 特斯拉磁共振成像检测小脑转移瘤（≤ 5 毫米）的灵敏度。

研究目的评估使用由对比增强三维-T1加权容积插值屏气检查（VIBE）得出的最大强度投影（MIP）图像是否能比源图像和二维-T1加权自旋回波（SE）图像更灵敏地检测到小（≤5 mm）脑转移瘤（BM）：我们对接受 1.5 特斯拉脑磁共振成像的脑转移瘤患者进行了单中心回顾性研究。两名阅读者分别统计了七组对比增强图像中的小BM数量：轴向二维-T1加权SE、三维-T1加权VIBE、2.5毫米厚-MIP T1加权VIBE和5毫米厚-MIP T1加权VIBE；矢状三维-T1加权VIBE、2.5毫米厚-MIP T1加权VIBE和5毫米厚-MIP T1加权VIBE。比较了每种图像类型检测到的病变总数。对灵敏度、假阴性和假阳性的平均比率以及平均差异进行了评估：结果：49 名患者共发现 403 个小 BM。结果发现：轴向 2D-T1 加权 SE 序列与所有其他成像技术的真阳性和假阴性数量存在显著差异；轴向 2D-T1 加权 SE 序列与轴向 3D-T1 加权 VIBE 序列的假阳性数量存在显著差异。灵敏度最高的两种图像类型是 2D-T1 加权 SE 和轴向 2.5 毫米厚 MIP T1 加权 VIBE。轴向 2D-T1 加权 SE 序列的灵敏度与所有其他序列有显著差异：结论：与原始图像相比，MIP 图像在检测小 BM 的灵敏度方面没有明显差异。

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来源期刊

Neuroradiology Journal NEUROIMAGING-

CiteScore

2.50

自引率

0.00%

发文量

101

期刊介绍： NRJ - The Neuroradiology Journal (formerly Rivista di Neuroradiologia) is the official journal of the Italian Association of Neuroradiology and of the several Scientific Societies from all over the world. Founded in 1988 as Rivista di Neuroradiologia, of June 2006 evolved in NRJ - The Neuroradiology Journal. It is published bimonthly.