Optical Coherence Tomography in the Assessment and Management of Cardiac Allograft Vasculopathy.

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Cardiology Reports Pub Date : 2024-08-01 Epub Date: 2024-06-12 DOI:10.1007/s11886-024-02078-7

Arka Chatterjee, Madhan Shanmugasundaram, Kwan S Lee, Toshinobu Kazui, Indranee N Rajapreyar, Deepak Acharya

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Abstract

Purpose of review: Cardiac Allograft vasculopathy (CAV) is a major barrier to improving outcomes after heart transplantation. Coronary angiography has very low sensitivity to detect early CAV and intravascular ultrasound (IVUS) only improves it to some extent. In this article, we detail the current evidence surrounding use of Optical Coherence tomography (OCT) in patients with CAV.

Recent findings: OCT has the ability to recognize CAV at earlier stages with intimal thickness < 150 μm, can characterize CAV in almost pathologic / microscopic detail - plaque characteristics are better visualized and novel early features such as layered fibrotic plaques and microchannels have been identified. Progression of CAV can be monitored also, with promise shown in automated serial measurements also. OCT has significantly advanced our understanding of the pathophysiology-as well as permits precise monitoring and surveillance of the disease. Potential treatment options could also be evaluated using OCT.

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光学相干断层扫描在心脏移植血管病变评估和管理中的应用。

综述目的：心脏移植血管病变（CAV）是改善心脏移植后预后的主要障碍。冠状动脉造影术检测早期 CAV 的灵敏度非常低，血管内超声（IVUS）也只能在一定程度上改善其灵敏度。在本文中，我们将详细介绍有关在 CAV 患者中使用光学相干断层扫描（OCT）的现有证据：光学相干断层扫描（OCT）有能力识别早期的 CAV，其内膜厚度可与血管超声（IVUS）相媲美。

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来源期刊

Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.20

自引率

2.70%

发文量

209

期刊介绍： The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.