Effects of traditional Chinese medicines on weight management among adults with overweight or obesity: A systematic review and network meta-analysis.

IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Obesity Science & Practice Pub Date : 2024-06-10 eCollection Date: 2024-06-01 DOI:10.1002/osp4.763
Meifang Chen, Jiaqi Liu
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Abstract

Increasing evidence has reported the anti-obesity effects of traditional Chinese medicines (TCMs) and their potential advantages in weight loss, such as fewer side effects and lower costs compared to the current recommended treatments like Western medicines. Previous review studies have examined the effects of a few commonly used TCM therapies such as acupuncture and herbal medicines on weight loss. This network meta-analysis (NMA) study aims to review and rank the effects of currently available TCMs on weight loss and to compare the effects of TCMs with different intervention durations. Eligible Randomized controlled trials (RCTs) conducted among Chinese adults with overweight or obesity were searched on electronic databases (PubMed, Embase, CNKI, WanFang, VIP, and SinoMed) up to 1 March 2023. Pairwise meta-analysis was performed to examine the pooled effects of TCMs on weight loss, and NMA was conducted to rank different types of TCMs. Subgroup analysis stratified by intervention duration was performed. Forty-six RCTs were eligible for inclusion in the review. The results showed that TCMs, especially when the treatment duration was ≤6 months, were more effective in both body weight and Body Mass Index (BMI) reduction than non-pharmacological interventions and placebo/no treatment. Acupotomy was ranked as the most effective TCM treatment in reducing both body weight and BMI. Traditional Chinese medicines have promising potential for weight loss and could be included in future clinical guidance as a standalone or supplementary treatment for obesity. Future studies need to further investigate under-researched TCMs, examine the long-term effects and safety of TCMs in obesity treatment, and validate the findings from this study among other ethnic populations.

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传统中药对超重或肥胖成人体重控制的影响:系统综述和网络荟萃分析。
越来越多的证据表明,传统中药具有抗肥胖的作用,而且与目前推荐的西药等治疗方法相比,传统中药在减肥方面具有副作用少、成本低等潜在优势。以往的综述研究考察了针灸和中药等几种常用中医疗法的减肥效果。这项网络荟萃分析(NMA)研究旨在对目前可用的中医药减肥效果进行回顾和排序,并比较不同干预持续时间的中医药减肥效果。研究人员在电子数据库(PubMed、Embase、CNKI、万方、VIP和SinoMed)中检索了截至2023年3月1日在中国超重或肥胖成人中进行的随机对照试验(RCT)。进行配对荟萃分析以检验中医药对减肥的总体效果,并对不同类型的中医药进行NMA排序。根据干预持续时间进行了分组分析。46项研究符合纳入研究的条件。结果显示,与非药物干预和安慰剂/不治疗相比,中医药在减轻体重和降低体质指数(BMI)方面更有效,尤其是当治疗时间≤6个月时。在减轻体重和降低体重指数方面,穴位疗法被评为最有效的中医疗法。中药在减肥方面具有广阔的前景,可作为肥胖症的独立或辅助治疗方法纳入未来的临床指南。今后的研究需要进一步调查研究不足的中药,检查中药在肥胖症治疗中的长期效果和安全性,并在其他种族人群中验证本研究的结果。
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来源期刊
Obesity Science & Practice
Obesity Science & Practice ENDOCRINOLOGY & METABOLISM-
CiteScore
4.20
自引率
4.50%
发文量
73
审稿时长
29 weeks
期刊最新文献
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