Interrelationship of Sarcopenia and Cardiovascular Diseases: A Review of Potential Mechanisms and Management.

IF 1.2 Q4 ENDOCRINOLOGY & METABOLISM Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2024-01-01 Epub Date: 2023-10-27 DOI:10.15605/jafes.039.01.03

Frederick Berro Rivera, Bettina Therese Escolano, Frances Micole Nifas, Sarang Choi, Genquen Philip Carado, Edgar Lerma, Krishnaswami Vijayaraghavan, Marc Gregory Yu

{"title":"Interrelationship of Sarcopenia and Cardiovascular Diseases: A Review of Potential Mechanisms and Management.","authors":"Frederick Berro Rivera, Bettina Therese Escolano, Frances Micole Nifas, Sarang Choi, Genquen Philip Carado, Edgar Lerma, Krishnaswami Vijayaraghavan, Marc Gregory Yu","doi":"10.15605/jafes.039.01.03","DOIUrl":null,"url":null,"abstract":"<p><p>Sarcopenia refers to an age-related reduction of lean body mass. It showed a reciprocal relationship with cardiovascular diseases. Thus, it is imperative to explore pathophysiological mechanisms explaining the relationship between sarcopenia and cardiovascular diseases, along with the clinical assessment, and associated management. In this review, we discuss how processes such as inflammation, oxidative stress, endothelial dysfunction, neural and hormonal modifications, as well as other metabolic disturbances influence sarcopenia as well as its association with cardiovascular diseases. Moreover, this review provides an overview of both non-pharmacological and pharmacological management for patients with sarcopenia and cardiovascular diseases, with a focus on the potential role of cardiovascular drugs to mitigate sarcopenia.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"39 1","pages":"69-78"},"PeriodicalIF":1.2000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163321/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the ASEAN Federation of Endocrine Societies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15605/jafes.039.01.03","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/10/27 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Sarcopenia refers to an age-related reduction of lean body mass. It showed a reciprocal relationship with cardiovascular diseases. Thus, it is imperative to explore pathophysiological mechanisms explaining the relationship between sarcopenia and cardiovascular diseases, along with the clinical assessment, and associated management. In this review, we discuss how processes such as inflammation, oxidative stress, endothelial dysfunction, neural and hormonal modifications, as well as other metabolic disturbances influence sarcopenia as well as its association with cardiovascular diseases. Moreover, this review provides an overview of both non-pharmacological and pharmacological management for patients with sarcopenia and cardiovascular diseases, with a focus on the potential role of cardiovascular drugs to mitigate sarcopenia.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

肌肉疏松症与心血管疾病的相互关系：潜在机制与管理综述。

肌肉疏松症是指与年龄有关的瘦体重减少。它与心血管疾病之间存在相互关系。因此，探索肌少症与心血管疾病之间关系的病理生理机制，以及临床评估和相关的治疗方法势在必行。在本综述中，我们将讨论炎症、氧化应激、内皮功能障碍、神经和荷尔蒙变化以及其他代谢紊乱等过程如何影响肌肉疏松症及其与心血管疾病的关系。此外，本综述还概述了针对肌肉疏松症和心血管疾病患者的非药物和药物治疗方法，重点是心血管药物在缓解肌肉疏松症方面的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of the ASEAN Federation of Endocrine Societies ENDOCRINOLOGY & METABOLISM-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.