Jiabin Xing, Qihan Lin, Sheng-Yi Zhuang, Gang Wu, Jiangshan Zhang, Hui Wang, Dan-Wei Zhang and Zhan-Ting Li
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引用次数: 0
Abstract
A hydrogen bonded calix[5]arene cavitand has been designed and prepared, which has a bowl-like cavity of about 0.85 nm width. The binding affinity of the container for ferrocene and eight of its derivatives in chloroform is modest. In a binary perfluoro-1-iodohexane and chloroform mixture (9 : 1 v/v), binding constants for the complexes of the seven fluorine-free guests increase by 14.0–144.1 times. In contrast, binding constants for the complexes of two guests that bear a perfluoroheptyl group do not exhibit similar increases. Similar enhancement of binding affinity can also be observed in binary solvents of perfluoro-1-iodobutane or perfluoro-1-iodooctane and chloroform. The results support that perfluoro-1-iodoalkanes in the cavity of the calix[5]arene container function as high-energy solvent molecules and their release into the bulk phase is the major driving force for enhanced inclusion by the calix[5]arene container of the fluorine-free guests.
期刊介绍:
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.