Application of green synthesized silver nanoparticles in Burn therapy: a review.

IF 1.5 4区 医学 Q4 CHEMISTRY, MEDICINAL Pharmazie Pub Date : 2024-05-15 DOI:10.1691/ph.2024.3045
A A Mohammed, A A Alqahtani, M M Ahmed
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引用次数: 0

Abstract

Silver nanoparticles (AgNPs), owing to their unusual characteristics, have been used in various pharmaceutical, cosmetic, and healthcare products. AgNPs, with their exceptional biological potential, exhibit antibacterial, antifungal, antiviral, anti-inflammatory, anticancer, and wound healing properties and have been extensively used in burn therapy. Several studies have established the use of silver nanoparticles in the treatment of burn injuries, resulting in reduced inflammation, quick tissue regeneration, and the remarkable creation of collagen fibers. Conventional physical and chemical techniques have synthesized AgNPs, but they appear to be highly costly and hazardous. Recently, there has been considerable interest in the synthesis of AgNPs using the green chemistry approach because of its tremendous benefits, including being non-toxic, low energy consumption, pollution-free, economical, environmentally friendly, and more sustainable. This review emphasizes the green synthesis of AgNPs using bacteria, fungi, plants, and other microorganisms and the current research related to the application of green synthesized AgNPs in burn therapy, including the biological aspects of AgNPs, their mode of action, and any possible detrimental effects.

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绿色合成银纳米粒子在烧伤治疗中的应用:综述。
银纳米粒子(AgNPs)因其不同寻常的特性,已被用于各种医药、化妆品和保健产品中。银纳米粒子具有卓越的生物潜力,具有抗菌、抗真菌、抗病毒、抗炎、抗癌和伤口愈合等特性,已被广泛用于烧伤治疗。多项研究证实,使用银纳米粒子治疗烧伤可减轻炎症反应,加快组织再生,并显著生成胶原纤维。传统的物理和化学技术已经合成了银纳米粒子,但这些技术似乎成本高昂且有害。最近,人们对使用绿色化学方法合成 AgNPs 产生了浓厚的兴趣,因为这种方法具有无毒、低能耗、无污染、经济、环保和可持续发展等巨大优势。本综述强调利用细菌、真菌、植物和其他微生物绿色合成 AgNPs,以及当前与绿色合成的 AgNPs 在烧伤治疗中的应用相关的研究,包括 AgNPs 的生物学特性、作用模式和可能的不利影响。
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来源期刊
Pharmazie
Pharmazie 医学-化学综合
CiteScore
3.10
自引率
0.00%
发文量
56
审稿时长
1.2 months
期刊介绍: The journal DiePharmazie publishs reviews, experimental studies, letters to the editor, as well as book reviews. The following fields of pharmacy are covered: Pharmaceutical and medicinal chemistry; Pharmaceutical analysis and drug control; Pharmaceutical technolgy; Biopharmacy (biopharmaceutics, pharmacokinetics, biotransformation); Experimental and clinical pharmacology; Pharmaceutical biology (pharmacognosy); Clinical pharmacy; History of pharmacy.
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