Antiretroviral therapy non-adherence and its association with psychosocial factors in Nigeria: comparative study of sexual minority and heterosexual men living with HIV.

IF 1.2 4区 医学 Q4 HEALTH POLICY & SERVICES Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2024-10-01 Epub Date: 2024-06-13 DOI:10.1080/09540121.2024.2366511
Olakunle Ayokunmi Oginni, Aderopo Igbekeleoluwa Adelola, Adedotun Ogunbajo, Onyedikachi Joseph Opara, Michael Akanji, Olanrewaju Ibikunle Ibigbami, Olusegun Temitope Afolabi, Adesanmi Akinsulore, Boladale Moyosore Mapayi, Samuel Kolawole Mosaku
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Abstract

Sexual minority men (gay, bisexual and other men who have sex with men; SMM) in Nigeria are disproportionately affected by HIV compared to heterosexual men. There is a dearth of research on the correlates of antiretroviral therapy (ART) non-adherence and correlates in both groups. The current study examined the associations of ART non-adherence with sociodemographic and psychosocial characteristics among a sample of Nigerian heterosexual and SMM. Between March and September 2014, we surveyed 120 SMM and 108 heterosexual men receiving ART in Lagos and Abuja, Nigeria. We specified univariate and multivariable linear regression models to examine correlates of ART non-adherence. We found that 50.8% and 29.6% of sexual minority and heterosexual men respectively self-reported ART non-adherence which was significantly associated with psychosocial factors such as stigma, depressive symptoms, and suicidality. Mental health care and psychosocial support should be incorporated into routine HIV care for Nigerian SMM living with HIV.

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尼日利亚不坚持抗逆转录病毒疗法及其与社会心理因素的关系:对感染艾滋病毒的性少数群体男子和异性恋男子的比较研究。
在尼日利亚,与异性恋男子相比,性少数男子(男同性恋、双性恋和其他男男性行为者;SMM)受艾滋病毒的影响尤为严重。关于这两个群体不坚持抗逆转录病毒疗法(ART)的相关性和关联性的研究还很缺乏。本研究调查了尼日利亚异性恋和SMM样本中不坚持抗逆转录病毒疗法与社会人口学和社会心理特征之间的关联。2014 年 3 月至 9 月间,我们在尼日利亚拉各斯和阿布贾对 120 名 SMM 和 108 名接受抗逆转录病毒疗法的异性恋男性进行了调查。我们建立了单变量和多变量线性回归模型来研究抗逆转录病毒疗法不依从的相关因素。我们发现,分别有 50.8% 和 29.6% 的性少数群体男性和异性恋男性自我报告不坚持抗逆转录病毒疗法,这与社会心理因素(如耻辱感、抑郁症状和自杀倾向)有显著关联。应将心理健康护理和社会心理支持纳入尼日利亚性少数群体男性艾滋病感染者的常规艾滋病护理中。
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