Prescriptions of opioid-containing drugs in patients with chronic cough.

IF 3.3 3区 医学 Q2 RESPIRATORY SYSTEM Therapeutic Advances in Respiratory Disease Pub Date : 2024-01-01 DOI:10.1177/17534666241259373
Michael Weiner, Ziyue Liu, Jonathan Schelfhout, Paul Dexter, Anna R Roberts, Ashley Griffith, Vishal Bali, Jessica Weaver
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Abstract

Background: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.

Objectives: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.

Design: Retrospective cohort study.

Methods: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a 'non-chronic cohort'. Student's t-test, Pearson's chi-square, and zero-inflated Poisson models were used.

Results: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.

Conclusion: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs' effectiveness.

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慢性咳嗽患者的含阿片类药物处方。
背景:慢性咳嗽(CC)影响着约 10% 的成年人,但人们对慢性咳嗽患者使用阿片类药物的情况还不甚了解:利用电子健康记录确定慢性咳嗽患者使用含阿片类止咳药(OCCS)处方的情况:设计:回顾性队列研究:通过对美国中西部地区的电子健康记录、诊断、处方和自然语言处理进行回顾性分析,确定了CC(至少有三次咳嗽就诊经历,第一次和最后一次就诊间隔56-120天)和 "非慢性队列"。研究采用了学生 t 检验、皮尔逊卡方检验和零膨胀泊松模型:结果:在23210名CC患者中,约20%的患者开具了OCCS处方;CC患者开具OCCS处方的几率是其他患者的两倍。在CC中,38%的医疗补助保险患者和15%的商业保险患者开具了OCCS药物处方:研究结果表明,阿片类药物在CC中发挥着重要作用,我们有机会进一步了解这些药物的有效性。
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来源期刊
CiteScore
6.90
自引率
0.00%
发文量
57
审稿时长
15 weeks
期刊介绍: Therapeutic Advances in Respiratory Disease delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of respiratory disease.
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