Deciphering the Drug Delivery Potential of Milk Exosome Nanovesicles for Aminobenzylpenicillin Therapeutic Efficacy against Contagious Staphylococcus Aureus in Bovine Mastitis (Adv. Biology 6/2024)

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-06-14 DOI:10.1002/adbi.202470063
Jitendra Kumar, Suneel Kumar Onteru, Dheer Singh
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Abstract

Staphylococcus Aureus

Treating contagious Staphylococcus aureus, the causative agent of bovine mastitis, is challenging with conventional antibiotics. In article number 2300519, Jitendra Kumar, Suneel Kumar Onteru, and Dheer Singh conduct cutting-edge research to deliver aminobenzylpenicillin into the mammary gland by harnessing the drug delivery potential of milk exosome nanovesicles. The advanced nanosystem demonstrate markedly superior therapeutic effectiveness compared to aminobenzylpenicillin when administered at the same dosage and treatment intervals, as illustrated on the cover page detailing the nanosystem.

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破译牛奶外泌体纳米微粒对氨苄青霉素治疗牛乳腺炎传染性金黄色葡萄球菌的给药潜力(生物学进展 6/2024)
金黄色葡萄球菌治疗传染性金黄色葡萄球菌是牛乳腺炎的致病菌,使用传统抗生素具有挑战性。在编号为 2300519 的文章中,Jitendra Kumar、Suneel Kumar Onteru 和 Dheer Singh 开展了前沿研究,利用牛奶外泌体纳米颗粒的给药潜力将氨苄青霉素送入乳腺。与氨苄青霉素相比,这种先进的纳米系统在相同剂量和治疗间隔的情况下显示出明显的治疗效果,详情请参见纳米系统的封面。
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