Brain metastasis originating from papillary renal cell carcinoma: A rare case report and literature review

Abdul Azis , Syarif Syarif , Saidah Rahmat , Moh. Anfasa Giffari Makkaraka , Willy Adhimarta , Faradilla Anwar
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Abstract

Papillary Renal Cell Carcinoma (PRCC) being the second most common histological type of Renal Cell Carcinoma (RCC). Although brain metastasis is rare in RCC, it often results in poorer outcomes compared to metastases in other locations. We present a case of brain metastasis originating from PRCC classified as pT1bN0M1. Subsequently, the patient underwent successful cytoreductive nephrectomy and pazopanib therapy as a follow-up systematic treatment. This case highlights the importance of urologists being aware of brain metastases that can develop in PRCC patients, which typically have a poorer outcome.

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源自乳头状肾细胞癌的脑转移:罕见病例报告和文献综述
乳头状肾细胞癌(PRCC)是肾细胞癌(RCC)中第二常见的组织学类型。虽然脑转移在RCC中很少见,但与其他部位的转移相比,脑转移往往导致较差的预后。我们介绍了一例源于PRC的脑转移病例,其分类为pT1bN0M1。随后,患者成功接受了细胞切除肾切除术,并接受了帕唑帕尼治疗作为后续的系统治疗。本病例强调了泌尿科医生对 PRCC 患者可能发生的脑转移(通常预后较差)保持警惕的重要性。
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