A Comprehensive Review on Microsponges Drug Delivery Systems

Sandesh Sah, Arti Kohri, Shivanand Patil
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Abstract

The special qualities of microsponges are making them a promising drug delivery system. These cross-linked, highly porous polymer particles have the capacity to encapsulate and release medications in a regulated fashion. Microsponges can effectively entrap both hydrophilic and hydrophobic drugs, improving their stability and preventing drug degradation, thanks to their large internal surface area and adjustable pore sizes. Innovative drug delivery devices known as microsponges have drawn a lot of interest from the pharmaceutical industry. The controlled and sustained release of medications is made possible by these porous, polymeric structures, which also minimise side effects and increase patient compliance. These systems also provide regulated release kinetics, which enhance bioavailability and minimise adverse effects. Because microsponges can be used topically or orally, they can be used for a wide range of therapeutic purposes. The potential of microsponges as adaptable drug delivery devices that could completely change the pharmaceutical formulation industry.
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微海绵给药系统综述
微海绵的特殊品质使其成为一种前景广阔的给药系统。这些交联的高多孔聚合物颗粒能够以可调节的方式封装和释放药物。由于微海绵具有较大的内表面积和可调节的孔径,因此可以有效地包裹亲水性和疏水性药物,提高药物的稳定性并防止药物降解。被称为微海绵的创新型给药装置引起了制药业的极大兴趣。这些多孔聚合物结构可以实现药物的可控和持续释放,还能最大限度地减少副作用,提高患者的依从性。这些系统还能提供可调节的释放动力学,从而提高生物利用率并将不良反应降至最低。由于微海绵可用于局部或口服,因此可用于多种治疗目的。微海绵作为适应性强的给药装置,可能会彻底改变药物制剂行业。
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