The photoprotective effectiveness of microemulsion gel made from an ethanol extract of kelakai root (Stenochlaena palustris (Brum. f) bedd.)

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES Pharmacy Education Pub Date : 2024-06-14 DOI:10.46542/pe.2024.246.134143
Dyera Forestryana, H. Ramadhan, Puteri Maulida
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Abstract

Background: Free radicals from sunlight have detrimental effects on the skin, such as black and dull colouration and dry- and easy-to-age skin. Prevention can be done by using antioxidants derived from plants as photoprotective. Kelakai root extract has a potent antioxidant activity of 19.06 ppm. Using typical preparations in the form of microemulsion gels protects the skin from free radicals.    Objective: This study aimed to determine the photoprotective effectiveness of the microemulsion gel preparation of kelakai root extract.     Method: The extraction method adopted maceration with 70% ethanol solvent. The microemulsion was incorporated into a gel dosage form with a concentration of 5%. The effectiveness of the photoprotective gel was measured using UV-Vis spectrophotometry, which included determining the value of the Sun Protector Factor (SPF), erythema transmission percentage (%Te), and pigmentation transmission percentage (%Tp).    Result: The results showed that the microemulsion gel of kelakai root extract with a concentration of 80 ppm had an SPF value of 9.816 with a %Te value of 9.591% and a %Tp value of 16.779%.     Conclusion: The microemulsion gel of the kelakai root extract has photoprotective effectiveness as a sunscreen in the sunblock category.
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从 Kelakai 根(Stenochlaena palustris (Brum. f) bedd.)
背景:阳光中的自由基会对皮肤产生有害影响,如皮肤变黑、无光泽、干燥和容易老化。从植物中提取抗氧化剂作为光保护剂可以起到预防作用。Kelakai 根提取物的抗氧化活性高达 19.06 ppm。使用微乳凝胶形式的典型制剂可以保护皮肤免受自由基的伤害。 研究目的本研究旨在确定凯拉凯根提取物微乳凝胶制剂的光保护效果。 方法:萃取方法采用 70% 丙酮浸渍法:提取方法采用 70% 的乙醇溶剂浸泡。将微乳剂加入浓度为 5%的凝胶剂型中。使用紫外可见分光光度法测定防晒凝胶的效果,包括确定防晒系数(SPF)值、红斑透射率(%Te)和色素沉着透射率(%Tp)。 结果显示结果表明,浓度为 80 ppm 的吉拉凯根提取物微乳液凝胶的 SPF 值为 9.816,Te 值为 9.591%,Tp 值为 16.779%。 结论柯拉开根提取物微乳液凝胶作为防晒霜具有防晒效果。
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来源期刊
Pharmacy Education
Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-
CiteScore
0.80
自引率
20.00%
发文量
174
期刊介绍: Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.
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