Current research of Assisted Reproductive Technology for women with early endometrial cancer and atypical endometrial hyperplasia after conservative treatment

Yan-le Jiang, Yan-ying Lin, Chen-xi Chen, Yu-xin Li, Huang-yan Xie, Bei-hong Zheng
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Abstract

As the incidence of endometrial cancer (EC) and atypical endometrial hyperplasia (AEH) has been increasing, and has shown young trend. It is crucial to study the fertility-preserving treatment of endometrial lesions and fertility-promoting protocols. Age, obesity, and irregular ovulation are not only high-risk factors for endometrial lesions but also key factors affecting female fertility. Assisted reproductive technology (ART) can significantly improve pregnancy outcomes in patients with AEH and EC after conservative treatment. Based on the existing studies, this article reviews the progress of research on pregnancy outcomes of ART and its influencing factors in such patients. It helps physicians in providing optimal fertility guidance.
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对早期子宫内膜癌和非典型子宫内膜增生症妇女保守治疗后采用辅助生殖技术的研究现状
随着子宫内膜癌(EC)和非典型子宫内膜增生症(AEH)发病率的不断上升,并呈现年轻化趋势。研究子宫内膜病变的保胎治疗和促排方案至关重要。年龄、肥胖和排卵不规律不仅是子宫内膜病变的高危因素,也是影响女性生育能力的关键因素。辅助生殖技术(ART)可显著改善保守治疗后 AEH 和 EC 患者的妊娠结局。本文在现有研究的基础上,回顾了辅助生殖技术在此类患者中的妊娠结局及其影响因素的研究进展。它有助于医生提供最佳的生育指导。
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