{"title":"CRISPR-CAS System: Current Applications and Future Prospect","authors":"A. Adinda, Irene Ruth Saputra, Rachel Maya","doi":"10.32539/sjm.v7i1.219","DOIUrl":null,"url":null,"abstract":"The CRISPR-Cas system is a revolutionary technology that has transformed gene editing and has the potential to revolutionize many fields. It is a bacterial immune system that can be programmed to recognize and cleave specific DNA sequences using Cas proteins and guide RNAs. This technology has numerous biotechnological and bioengineering applications and is simpler to design with high targeting efficiency and multiplex editing capability compared to older gene editing technologies. This review aims to explore the general application, impact on molecular biology and medicine, limitations, and future potential of the CRISPR-Cas system. With its potential to revolutionize medicine, agriculture, and environmental science, the CRISPR-Cas system is a powerful gene editing tool that offers hope for a wide range of applications.","PeriodicalId":252478,"journal":{"name":"Sriwijaya Journal of Medicine","volume":" 11","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sriwijaya Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32539/sjm.v7i1.219","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The CRISPR-Cas system is a revolutionary technology that has transformed gene editing and has the potential to revolutionize many fields. It is a bacterial immune system that can be programmed to recognize and cleave specific DNA sequences using Cas proteins and guide RNAs. This technology has numerous biotechnological and bioengineering applications and is simpler to design with high targeting efficiency and multiplex editing capability compared to older gene editing technologies. This review aims to explore the general application, impact on molecular biology and medicine, limitations, and future potential of the CRISPR-Cas system. With its potential to revolutionize medicine, agriculture, and environmental science, the CRISPR-Cas system is a powerful gene editing tool that offers hope for a wide range of applications.
CRISPR-Cas系统是一项革命性技术，它改变了基因编辑技术，并有可能给许多领域带来变革。它是一种细菌免疫系统，可通过编程利用 Cas 蛋白和引导 RNA 识别并切割特定的 DNA 序列。这项技术在生物技术和生物工程领域有着广泛的应用，与旧的基因编辑技术相比，它的设计更简单，具有高靶向效率和多重编辑能力。本综述旨在探讨 CRISPR-Cas 系统的一般应用、对分子生物学和医学的影响、局限性和未来潜力。CRISPR-Cas 系统具有彻底改变医学、农业和环境科学的潜力，是一种强大的基因编辑工具，为广泛的应用带来了希望。
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