Suturing and Closure of Diaphragma Sella to Augment Sellar Floor Repair after Endonasal Endoscopic Resection of Large Pituitary Adenoma

Sushant K. Sahoo, Murali K. Bethanbhatla, S. Dhandapani
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Abstract

Abstract Background  Large pituitary adenoma often pushes the diaphragma sella and extends to the suprasellar compartment. The thinned out diaphragma may get opened during endonasal endoscopic surgery and pose high risk for cerebrospinal fluid (CSF) leak. Such larger defects are difficult to plug with fat graft that tends to slip in to the subarachnoid space. Here, we describe a unique technique of closure of diaphragma sella that augment repair of the skull base in such cases. Method  The free edge of diaphragma sella was sutured with the anterior tuberculum sella dura in five cases of large pituitary adenoma that needed extra arachnoidal resection. Suturing was done with 6-0 prolene using endoscopic needle holder that converted a large diaphragm defect in to a smaller arachnoid rent and was easily plugged with fat graft. Result  None of these patients had postoperative CSF leak. Conclusion  Though technically difficult, direct repair of the diaphragma sella is possible. This augments the skull base reconstruct and effectively reduces the chances of postoperative CSF leak.
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鼻内镜下切除巨大垂体腺瘤后缝合膈肌以增强泽兰底修补术
摘要 背景 大型垂体腺瘤通常会压迫蝶鞍膈,并延伸至鞍上区。在进行鼻内镜手术时,变薄的膈肌可能会被打开,造成脑脊液(CSF)漏的高风险。这种较大的缺损很难用脂肪移植堵塞,因为脂肪移植往往会滑入蛛网膜下腔。在此,我们介绍一种独特的蝶鞍膈闭合技术,该技术可增强此类病例的颅底修复。方法 在五例需要额外蛛网膜切除的巨大垂体腺瘤病例中,将蝶鞍膈游离缘与硬脑膜前结节缝合。使用内窥镜持针器,用 6-0 prolene 进行缝合,将大的膈肌缺损转化为较小的蛛网膜裂隙,并很容易用脂肪移植堵塞。结果 这些患者术后均无 CSF 渗漏。结论 尽管技术上有难度,但直接修复颅膈是可行的。这可以增强颅底重建,有效降低术后 CSF 渗漏的几率。
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