Surgical procedures and complications in placement of totally implantable venous access port in pediatric hemophilia patients: A retrospective analysis

IF 2.1 4区 医学 Q3 HEMATOLOGY Blood Cells Molecules and Diseases Pub Date : 2024-06-07 DOI:10.1016/j.bcmd.2024.102862
Wei Cheng , Jinrui Zhang , Xipeng Wang , Guoqing Liu , Wanru Yao , Chunli Wang , Runhui Wu , Zhiqiang Li
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Abstract

This retrospective study at Beijing Children's Hospital (2020–2023) analyzed surgical procedures and complications in 24 pediatric hemophilia patients undergoing Totally Implantable Venous Access Port (TIVAP) insertion, primarily in the right jugular vein (RJV). We detailed the surgical process, including patient demographics and intraoperative imaging use. The choice of the RJV for TIVAP placement was influenced by its larger diameter and superficial anatomical position, potentially reducing risks like thrombosis and infection. Our findings support the RJV as a safer alternative for port placement in pediatric patients, aligning with current literature. Statistical analysis revealed no significant correlation between complications and baseline characteristics like weight and diagnosis type. However, the length of hospital stay and implant brand were significant risk factors for catheter or port displacement and removal. The limited patient number may introduce bias, suggesting a need for further studies with larger samples. Despite a 14.7 %–33 % complication rate and 5 port removals, the advantages of TIVAP, including reliable venous access, reduced discomfort, and treatment convenience, were evident. Most complications improved with symptomatic treatment, and there were no deaths due to port-related complications, underscoring the impact of TIVAP on improving pediatric hemophilia treatment.

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小儿血友病患者植入全植入式静脉通路端口的手术过程和并发症:回顾性分析
这项在北京儿童医院进行的回顾性研究(2020-2023 年)分析了 24 例接受全植入式静脉通路端口(TIVAP)植入术(主要在右颈静脉(RJV))的小儿血友病患者的手术过程和并发症。我们详细介绍了手术过程,包括患者的人口统计学特征和术中使用的成像技术。选择 RJV 进行 TIVAP 置入是受其较大直径和浅表解剖位置的影响,这可能会降低血栓形成和感染等风险。我们的研究结果支持将 RJV 作为儿科患者更安全的端口置入替代方案,这与目前的文献一致。统计分析显示,并发症与体重和诊断类型等基线特征之间没有明显的相关性。不过,住院时间和植入物品牌是导管或端口移位和移除的重要风险因素。有限的患者人数可能会造成偏差,因此有必要进行更大规模的研究。尽管并发症发生率为14.7%-33%,且有5个端口被移除,但TIVAP的优势显而易见,包括可靠的静脉通路、减少不适感和治疗方便。大多数并发症在对症治疗后都得到了改善,没有人因端口相关并发症而死亡,这凸显了TIVAP对改善小儿血友病治疗的影响。
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来源期刊
CiteScore
4.90
自引率
0.00%
发文量
42
审稿时长
14 days
期刊介绍: Blood Cells, Molecules & Diseases emphasizes not only blood cells, but also covers the molecular basis of hematologic disease and studies of the diseases themselves. This is an invaluable resource to all those interested in the study of hematology, cell biology, immunology, and human genetics.
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