Neonatal and infant infection with SARS-CoV-2

IF 3.2 3区 医学 Q1 OBSTETRICS & GYNECOLOGY Seminars in perinatology Pub Date : 2024-06-01 DOI:10.1016/j.semperi.2024.151922
Logan P. Grimes , Jeffrey S. Gerber
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Abstract

Despite the substantial body of investigative work describing the Coronavirus Disease 2019 (COVID-19) pandemic, its impact on neonates and infants remains less well characterized. Here, we review the data on epidemiology of COVID-19 in this population. Widespread use of universal testing for SARS-CoV-2 among pregnant persons presenting for delivery complicates interpretation of the risks of perinatal exposure. While many neonates and infants with COVID-19 are well-appearing or have only mild signs of illness, factors such as preterm birth, low birth weight, and medical comorbidities increase the risk of severe infection. We highlight potential protective maternal factors, summarize treatment options and discuss vaccine development. Higher quality data are needed to better inform our understanding of COVID-19 in neonates and infants.

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新生儿和婴儿感染 SARS-CoV-2
尽管大量的调查工作描述了冠状病毒病 2019(COVID-19)大流行的情况,但其对新生儿和婴儿的影响仍然没有得到很好的描述。在此,我们回顾了COVID-19在这一人群中的流行病学数据。在待产孕妇中广泛使用 SARS-CoV-2 通用检测方法使围产期暴露风险的解释变得复杂。虽然许多感染 COVID-19 的新生儿和婴儿表现良好或仅有轻微病症,但早产、出生体重低和合并症等因素会增加严重感染的风险。我们强调了潜在的母体保护因素,总结了治疗方案并讨论了疫苗的开发。我们需要更高质量的数据来更好地了解新生儿和婴儿的 COVID-19 感染情况。
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来源期刊
Seminars in perinatology
Seminars in perinatology 医学-妇产科学
CiteScore
5.80
自引率
2.90%
发文量
97
审稿时长
6-12 weeks
期刊介绍: The purpose of each issue of Seminars in Perinatology is to provide authoritative and comprehensive reviews of a single topic of interest to professionals who care for the mother, the fetus, and the newborn. The journal''s readership includes perinatologists, obstetricians, pediatricians, epidemiologists, students in these fields, and others. Each issue offers a comprehensive review of an individual topic, with emphasis on new developments that will have a direct impact on their practice.
期刊最新文献
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