Impact of the COVID-19 lockdown on the O'Sullivan test and gestational diabetes mellitus diagnosis in pregnant Spanish women

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Atencion Primaria Pub Date : 2024-06-17 DOI:10.1016/j.aprim.2024.103006
Encarnación Ruiz Peláez , Esperanza Macarena Hurtado Algar , Teresa Martínez la Torre , Javier Sánchez-Romero , Iván Hernández-Caravaca
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Abstract

Objective

To analyze the impact of COVID-19 lockdown on serum glucose levels of pregnant women.

Design

A retrospective analysis of O'Sullivan test in pregnant women who underwent COVID-19 lockdown compared to controls.

Site

Poniente Primary Health Care center in Córdoba (Spain).

Participants

235 pregnant women from 23+0 to 25+0 weeks of gestation without diabetes mellitus.

Interventions

Gestational diabetes mellitus screening with O'Sullivan test and 3-h oral glucose tolerance test.

Main measurements

Pregnant women who underwent gestational diabetes mellitus screening with O'Sullivan test before (control group) and during COVID-19 Lockdown (Lockdown group) in Córdoba (Spain) were investigated. Lockdown group was divided in early and late lockdown. An additional, control group from data of the same months of the Lockdown in the previous year were recorded to discarded seasonally (adjusted seasonally control) this group was also divided in early and late seasonally adjusted.

A logistic regression model for O'Sullivan test has been performed to analyze potential cofounders. Kolgomorov–Smirnov and Kruskal–Wallis test comparing pregnant women who underwent COVID-19 lockdown with the two types of controls.

Results

Statistically significant differences were found in serum glucose after O'Sullivan test between lockdown group and control group (123.51 ± 26.02 mg/dL and 112.86 ± 31.28 mg/dL; p = 0.017). When early lockdown group and control group were compared no differences were found (119.64 ± 26.18 mg/dL vs. 112.86 ± 31.28 mg/dL; p > 0.05) whereas differences were observed in late lockdown group and control group (127.22 ± 25.59 mg/dL vs. 112.86 ± 31.28 mg/dL; p = 0.009). Statistical trends were also found between lockdown group and seasonally adjusted group and between lockdown and late seasonally adjusted group (p = 0.089). A higher proportion of positive O'Suvillan pregnant women who were subsequently diagnosed with GDM were found in lockdown group compared to the seasonally adjusted control group (60% vs. 26.06% respectively; p < 0.05).

Conclusions

The COVID-19 lockdown was associated with an increase in serum glucose levels after the O'Sullivan test as well as a higher GDM diagnosis risk in pregnant women. The findings of our study emphasize the essential requirement for comprehensive maternal services and the accessibility to community's health assets during future lockdown scenarios to pregnant women.

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COVID-19 封锁对西班牙孕妇奥沙利文测试和妊娠糖尿病诊断的影响。
目的:分析COVID-19锁定对孕妇血清葡萄糖水平的影响:分析 COVID-19 禁用对孕妇血清葡萄糖水平的影响:设计:与对照组相比,对接受 COVID-19 封闭治疗的孕妇的奥沙利文试验进行回顾性分析。地点:科尔多瓦(西班牙)Poniente初级卫生保健中心。参与者:235名妊娠23+0周至25+0周、无糖尿病的孕妇:干预措施:通过奥沙利文试验和 3 小时口服葡萄糖耐量试验进行妊娠糖尿病筛查:调查了在科尔多瓦(西班牙)接受奥沙利文试验前(对照组)和 COVID-19 禁闭期间(禁闭组)进行妊娠糖尿病筛查的孕妇。禁闭组分为早期禁闭和晚期禁闭。另外,还记录了前一年封锁期间同月的对照组数据,并按季节将其剔除(按季节调整的对照组),该组也按季节调整分为早期和晚期。奥沙利文检验的逻辑回归模型用于分析潜在的共同始作俑者。将接受 COVID-19 封闭治疗的孕妇与两种对照组进行了 Kolgomorov-Smirnov 和 Kruskal-Wallis 检验:禁产组与对照组在奥沙利文试验后的血清葡萄糖差异有统计学意义(123.51±26.02mg/dL 和 112.86±31.28mg/dL;P=0.017)。锁定早期组与对照组比较未发现差异(119.64±26.18mg/dL vs. 112.86±31.28mg/dL;p>0.05),而锁定晚期组与对照组比较则发现差异(127.22±25.59mg/dL vs. 112.86±31.28mg/dL;p=0.009)。锁定组与季节调整组之间以及锁定组与晚期季节调整组之间也发现了统计趋势(P=0.089)。与季节调整对照组相比,锁定组中奥苏维兰阳性孕妇随后被诊断为 GDM 的比例更高(分别为 60% 对 26.06%;P 结论:COVID-19 禁产与奥沙利文试验后血清葡萄糖水平升高以及孕妇被诊断为 GDM 的风险升高有关。我们的研究结果强调,在未来的封锁情况下,孕妇必须获得全面的孕产妇服务和社区的医疗资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Atencion Primaria
Atencion Primaria 医学-医学:内科
CiteScore
2.90
自引率
8.00%
发文量
156
审稿时长
33 days
期刊介绍: Atención Primaria es una revista que publica trabajos de investigación relativos al ámbito de la atención primaria de salud. Desde el punto de vista conceptual, Atención Primaria asume el nuevo modelo de atención primaria de salud, orientado no sólo a la curación de la enfermedad, sino también a su prevención y a la promoción de la salud, tanto en el plano individual como en el de la familia y la comunidad. En estos nuevos aspectos que definen el modelo de atención primaria de salud es en los que se centran los trabajos de investigación que publica Atención Primaria, la primera revista de originales española creada para recoger y difundir la producción científica realizada desde los centros de atención primaria de salud sobre cuestiones como protocolización de la asistencia, programas de prevención, seguimiento y control de pacientes crónicos, organización y gestión de la asistencia primaria, entre otros.
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