Assessing Excess Mortality of Baby Boomers from the COVID-19 Pandemic: Taiwan Omicron-naïve Cohort.

IF 3.8 4区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Epidemiology and Global Health Pub Date : 2024-09-01 Epub Date: 2024-06-20 DOI:10.1007/s44197-024-00262-0
Ting-Yu Lin, Chen-Yang Hsu, Amy Ming-Fang Yen, Sam Li-Sheng Chen, Tony Hsiu-Hsi Chen
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Abstract

Background: Asia's elderly Baby Boomer demographic (born between 1946 and 1964) faced a huge problem during the COVID-19 pandemic due to increased all-cause mortality. We aimed to provide a unique Taiwan situation regarding the impact of Baby Boomers on excess mortalities from all causes relative to non-Baby Boomers throughout distinct times of SARS-CoV-2 mutations during the COVID-19 pandemic.

Methods: We used the Poisson time series design with a Bayesian directed acyclic graphic approach to build the background mortality prior to the COVID-19 pandemic between 2015 and 2019. It was then used for predicting the expected all-cause deaths compared to the reported figures during the COVID-19 pandemic period based on Taiwan residents, an Omicron-naïve cohort.

Results: Baby Boomers experienced a 2% negative excess mortality in 2020 (Wuhan/D614G) and a 4% excess mortality in 2021 (Alpha/Delta) with a rising background mortality trend whereas non-Baby Boomers showed the corresponding figures of 4% negative excess and 1% excess with a stable trend. Baby Boomer and non-Baby Boomer excess mortality soared to 9% (95% CI: 7-10%) and 10% (95% CI: 9-11%), respectively, during the epidemic Omicron period from January to June 2022. Surprisingly, Baby Boomers aged 58-76 experienced the same 9% excess mortality as non-Baby Boomers aged 77 and beyond. Non-COVID-19 deaths were more prevalent among Baby Boomers than non-Baby Boomers (33% vs. 29%).

Conclusion: Baby Boomers were more likely to die from COVID-19 in early pandemic and had more non-COVID-19 deaths in late pandemic than older non-Baby Boomers demonstrated in Taiwan Omicron-naïve cohort. For this vulnerable population, adequate access to medical care and medical capacity require more consideration.

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评估婴儿潮一代在 COVID-19 大流行中的超额死亡率:台湾 Omicron-naïve队列。
背景:在 COVID-19 大流行期间,亚洲的 "婴儿潮 "一代老年人口(1946 年至 1964 年出生)因全因死亡率增加而面临巨大问题。我们的目的是提供一个独特的台湾情况,说明在 COVID-19 大流行期间,在 SARS-CoV-2 变异的不同时期,相对于非婴儿潮一代,婴儿潮一代对各种原因造成的超额死亡率的影响:我们使用泊松时间序列设计和贝叶斯有向无环图方法,建立了 2015 年至 2019 年 COVID-19 大流行之前的背景死亡率。然后,根据台湾居民(Omicron-naïve 队列)的数据,预测 COVID-19 大流行期间预计的全因死亡人数:婴儿潮一代在 2020 年(武汉/D614G)和 2021 年(阿尔法/德尔塔)的负超额死亡率分别为 2%和 4%,且背景死亡率呈上升趋势;而非婴儿潮一代的负超额死亡率和超额死亡率分别为 4%和 1%,且趋势稳定。在 2022 年 1 月至 6 月流行的 Omicron 期间,婴儿潮一代和非婴儿潮一代的超额死亡率分别飙升至 9%(95% CI:7-10%)和 10%(95% CI:9-11%)。令人惊讶的是,58-76 岁的婴儿潮一代与 77 岁及以上的非婴儿潮一代的超额死亡率相同,均为 9%。与非婴儿潮一代人相比,婴儿潮一代人中非 COVID-19 死亡的比例更高(33% 对 29%):结论:与年龄较大的非婴儿潮一代相比,婴儿潮一代在大流行早期更有可能死于 COVID-19,在大流行晚期死于非 COVID-19 的人数也更多。对这一易感人群而言,需要更多地考虑是否有足够的医疗服务和医疗能力。
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来源期刊
CiteScore
10.70
自引率
1.40%
发文量
57
审稿时长
19 weeks
期刊介绍: The Journal of Epidemiology and Global Health is an esteemed international publication, offering a platform for peer-reviewed articles that drive advancements in global epidemiology and international health. Our mission is to shape global health policy by showcasing cutting-edge scholarship and innovative strategies.
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