The Association of Cerebral Oxygen Desaturation with Postoperative Cognitive Dysfunction in Older Patients: A Review.

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY Clinical Interventions in Aging Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI:10.2147/CIA.S462471

Chun-Yan Zhang, Yu-Shen Yang, Meng-Qin Pei, Xin-Li Chen, Wei-Can Chen, He-Fan He

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Abstract

Postoperative cognitive dysfunction (POCD) is a neurological complication associated with surgery and anesthesia that is commonly observed in older patients, and it can significantly affect patient prognosis and survival. Therefore, predicting and preventing POCD is important. Regional cerebral oxygen saturation (rSO₂) reflects cerebral perfusion and oxygenation, and decreased intraoperative cerebral oxygen saturation has been reported to increase the risk of POCD. In this review, we elucidated the important relationship between the decline in rSO2 and risk of POCD in older patients. We also emphasized the importance of monitoring rSO2 during surgery to predict and prevent adverse perioperative cognitive outcomes. The findings reveal that incorporating intraoperative rSO2 monitoring into clinical practice has potential benefits, such as protecting cognitive function, reducing perioperative adverse outcomes, and ultimately improving the overall quality of life of older adults.

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大脑缺氧与老年患者术后认知功能障碍的关系：综述。

术后认知功能障碍（POCD）是一种与手术和麻醉相关的神经系统并发症，常见于老年患者，会严重影响患者的预后和生存。因此，预测和预防 POCD 非常重要。区域脑氧饱和度（rSO2）反映了脑灌注和氧合情况，有报道称术中脑氧饱和度降低会增加 POCD 的风险。在这篇综述中，我们阐明了老年患者 rSO2 下降与 POCD 风险之间的重要关系。我们还强调了在手术期间监测 rSO2 以预测和预防围术期不良认知结果的重要性。研究结果表明，将术中 rSO2 监测纳入临床实践具有潜在的益处，如保护认知功能、减少围手术期不良后果，并最终改善老年人的整体生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Interventions in Aging GERIATRICS & GERONTOLOGY-

CiteScore

6.80

自引率

2.80%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Clinical Interventions in Aging, is an online, peer reviewed, open access journal focusing on concise rapid reporting of original research and reviews in aging. Special attention will be given to papers reporting on actual or potential clinical applications leading to improved prevention or treatment of disease or a greater understanding of pathological processes that result from maladaptive changes in the body associated with aging. This journal is directed at a wide array of scientists, engineers, pharmacists, pharmacologists and clinical specialists wishing to maintain an up to date knowledge of this exciting and emerging field.