Green synthesis of glutaramides, piperidino[1,2-a]benzimidazol-1-ones and N-cyclopentenyl benzimidazolones enabled by microwave assisted domino reactions of cyclic 2-diazo-1,3-diketones with aniline derivatives†

Cheng Zhao , Xiao-Wei Hu , Yi-Bin Xu , Xiong-Wei Liu , You-Ping Tian , Yun-Lin Liu
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Abstract

Microwave-assisted divergent domino reactions between cyclic 2-diazo-1,3-diketones and aniline derivatives selectively leading to either glutaramides, piperidino[1,2-a]benzimidazol-1-ones or N-cyclopentenyl benzimidazolones are described. This synthetic protocol features easy operation, a short reaction time, and environmental friendliness.

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通过环状 2-重氮-1,3-二酮与苯胺衍生物的微波辅助多米诺反应实现戊二酰胺、哌啶并[1,2-a]苯并咪唑-1-酮和 N-环戊烯基苯并咪唑酮的绿色合成
介绍了微波辅助下环状 2-重氮-1,3-二酮与苯胺衍生物之间的多米诺分化反应,该反应可选择性地生成戊二酰胺、哌啶并[1,2-a]苯并咪唑-1-酮或 N-环戊烯基苯并咪唑酮。该合成方案具有操作简便、反应时间短和环保等特点。
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