Intraindividual Comparison of Dose Reduction and Coronary Calcium Scoring Accuracy Using Kilovolt-independent and Tin Filtration CT Protocols.

IF 3.8 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiology. Cardiothoracic imaging Pub Date : 2024-06-01 DOI:10.1148/ryct.230246
Salma Zook, Bhupendar Tayal, Kristian Kragholm, Ola Abdelkarim, Diana Tran, Myra Cocker, Juan Carlos Ramirez-Giraldo, Kristina Hallam, Colleen Sexton, Stephanie Johnson, Su Min Chang
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Abstract

Purpose To investigate the ability of kilovolt-independent (hereafter, kV-independent) and tin filter spectral shaping to accurately quantify the coronary artery calcium score (CACS) and radiation dose reductions compared with the standard 120-kV CT protocol. Materials and Methods This prospective, blinded reader study included 201 participants (mean age, 60 years ± 9.8 [SD]; 119 female, 82 male) who underwent standard 120-kV CT and additional kV-independent and tin filter research CT scans from October 2020 to July 2021. Scans were reconstructed using a Qr36f kernel for standard scans and an Sa36f kernel for research scans simulating artificial 120-kV images. CACS, risk categorization, and radiation doses were compared by analyzing data with analysis of variance, Kruskal-Wallis test, Mann-Whitney test, Bland-Altman analysis, Pearson correlations, and κ analysis for agreement. Results There was no evidence of differences in CACS across standard 120-kV, kV-independent, and tin filter scans, with median CACS values of 1 (IQR, 0-48), 0.6 (IQR, 0-58), and 0 (IQR, 0-51), respectively (P = .85). Compared with standard 120-kV scans, kV-independent and tin filter scans showed excellent correlation in CACS values (r = 0.993 and r = 0.999, respectively), with high agreement in CACS risk categorization (κ = 0.95 and κ = 0.93, respectively). Standard 120-kV scans had a mean radiation dose of 2.09 mSv ± 0.84, while kV-independent and tin filter scans reduced it to 1.21 mSv ± 0.85 and 0.26 mSv ± 0.11, cutting doses by 42% and 87%, respectively (P < .001). Conclusion The kV-independent and tin filter research CT acquisition techniques showed excellent agreement and high accuracy in CACS estimation compared with standard 120-kV scans, with large reductions in radiation dose. Keywords: CT, Cardiac, Coronary Arteries, Radiation Safety, Coronary Artery Calcium Score, Radiation Dose Reduction, Low-Dose CT Scan, Tin Filter, kV-Independent Supplemental material is available for this article. © RSNA, 2024.

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使用独立于千伏和锡滤 CT 方案的剂量降低和冠状动脉钙化评分准确性的个体内比较。
目的 研究千伏独立型(以下简称千伏独立型)和锡滤波器频谱整形与标准 120 千伏 CT 方案相比,准确量化冠状动脉钙化评分 (CACS) 和减少辐射剂量的能力。材料和方法 这项前瞻性、盲人阅读研究纳入了 201 名参与者(平均年龄为 60 岁 ± 9.8 [SD];119 名女性,82 名男性),他们在 2020 年 10 月至 2021 年 7 月期间接受了标准 120-kV CT 以及额外的 kV 独立型和锡滤波研究 CT 扫描。标准扫描使用 Qr36f 内核重建,研究扫描使用 Sa36f 内核模拟人工 120-kV 图像。通过方差分析、Kruskal-Wallis 检验、Mann-Whitney 检验、Bland-Altman 分析、Pearson 相关性和 κ 一致性分析分析数据,比较 CACS、风险分类和辐射剂量。结果 没有证据表明标准 120-kV、独立 kV 和锡滤波器扫描的 CACS 存在差异,CACS 中位值分别为 1(IQR,0-48)、0.6(IQR,0-58)和 0(IQR,0-51)(P = .85)。与标准 120-kV 扫描相比,kV 独立扫描和锡滤波器扫描的 CACS 值显示出极好的相关性(r = 0.993 和 r = 0.999),CACS 风险分类的一致性也很高(κ = 0.95 和 κ = 0.93)。标准 120 kV 扫描的平均辐射剂量为 2.09 mSv ± 0.84,而独立 kV 扫描和锡滤波器扫描的平均辐射剂量则分别降至 1.21 mSv ± 0.85 和 0.26 mSv ± 0.11,剂量分别减少了 42% 和 87%(P < .001)。结论 与标准 120-kV 扫描相比,独立于 kV 和锡滤波研究 CT 采集技术在 CACS 估算方面显示出极佳的一致性和高准确性,并大幅降低了辐射剂量。关键词CT,心脏,冠状动脉,辐射安全,冠状动脉钙化评分,辐射剂量减少,低剂量CT扫描,锡滤波器,独立于kV的CT扫描 本文有补充材料。© RSNA, 2024.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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