Stroke outcomes following cardiac and aortic surgery are improved by the involvement of a stroke team

IF 4.4 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL European Journal of Clinical Investigation Pub Date : 2024-06-29 DOI:10.1111/eci.14275
Amer Harky, Vanessa Jane Chow, Calum Voller, Kartik Goyal, Matthew Shaw, Anurodh Bhawnani, Ayman Kenawy, Ian Wilson, Gregory Y. H. Lip, Mark Field, Manoj Kuduvalli
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Abstract

Objectives

Post-cardiac and aortic surgery stroke is often underreported. We detail our single-centre experience the following introduction of comprehensive consultant-led daily stroke service, to demonstrate the efficacy of a stroke team in recovery from stroke following cardiac and aortic surgeries.

Methods

This retrospective, single-centre observational cohort study analysed consecutive patients undergoing cardiac and aortic surgery at our institution from August 2014 to December 2020. Main outcomes included stroke rate, predictors of stroke, and neurological deficit resolution or persistence at discharge and clinic follow-up.

Results

A total of 12,135 procedures were carried out in the reference period. Among these, 436 (3.6%) suffered a stroke. Overall survival to discharge and follow-up were 86.0% and 84.0% respectively. Independent risk factors for post-operative stroke included advanced age (OR 1.033, 95% CI [1.023, 1.044], p < .001), female sex (OR 1.491, 95% [1.212, 1.827], p < .001), history of previous cardiac surgeries (OR 1.670, 95% CI [1.239, 2.218], p < .001), simultaneous coronary artery bypass graft + valve procedures (OR 1.825, 95% CI [1.382, 2.382], p < .001) and CPB time longer than 240 min (OR 3.384, 95% CI [2.413, 4.705], p < .001). Stroke patients managed by the multidisciplinary team demonstrated significantly higher rates of survival at discharge (87.3% vs. 61.9%, p = .001).

Conclusions

Perioperative stroke can be debilitating immediately long term. The involvement of specialist stroke teams plays a key role in reducing the long-term burden and mortality of this condition.

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心脏和主动脉手术后的卒中预后可通过卒中团队的参与得到改善。
目的:心脏手术和主动脉手术后中风的报道往往不足。我们详细介绍了我们单中心在引入顾问主导的全面日常卒中服务后的经验,以证明卒中团队在心脏和主动脉手术后卒中恢复中的有效性:这项回顾性、单中心观察性队列研究分析了 2014 年 8 月至 2020 年 12 月期间在我院接受心脏和主动脉手术的连续患者。主要结果包括卒中率、卒中的预测因素以及出院和门诊随访时神经功能缺损的缓解或持续情况:结果:参照期内共进行了 12 135 例手术。结果:参照期内共进行了 12 135 例手术,其中 436 例(3.6%)发生了中风。出院和随访的总生存率分别为 86.0% 和 84.0%。术后中风的独立风险因素包括高龄(OR 1.033,95% CI [1.023,1.044],P 结论:术后中风可能会对患者的身体造成损害:围手术期中风可能会立即导致长期衰弱。卒中专科团队的参与对减少这种疾病的长期负担和死亡率起着关键作用。
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来源期刊
CiteScore
9.50
自引率
3.60%
发文量
192
审稿时长
1 months
期刊介绍: EJCI considers any original contribution from the most sophisticated basic molecular sciences to applied clinical and translational research and evidence-based medicine across a broad range of subspecialties. The EJCI publishes reports of high-quality research that pertain to the genetic, molecular, cellular, or physiological basis of human biology and disease, as well as research that addresses prevalence, diagnosis, course, treatment, and prevention of disease. We are primarily interested in studies directly pertinent to humans, but submission of robust in vitro and animal work is also encouraged. Interdisciplinary work and research using innovative methods and combinations of laboratory, clinical, and epidemiological methodologies and techniques is of great interest to the journal. Several categories of manuscripts (for detailed description see below) are considered: editorials, original articles (also including randomized clinical trials, systematic reviews and meta-analyses), reviews (narrative reviews), opinion articles (including debates, perspectives and commentaries); and letters to the Editor.
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